Gas gangrene is a disease that is identical to the incidence of type 2 diabetes mellitus with the characteristics of muscle necrosis / myonecrosis and is a very deadly infection of the inner soft tissues, often caused by gram-positive bacteria such as Staphylococcus aureus, Clostridium perifingens. Diabetes mellitus is a collection of symptoms caused by disturbances in the balance between carbohydrates, fats and proteins caused by absolute or relative insulin deficiency, causing hyperglycemia and glucosuria. to describe the profile of patients with gas gangrene pedis caused by type II diabetes mellitus obtained from the results of secondary data research at Bhayangkara Hospital Kediri Period January 2021 - March 2022. This study is an observational study (Non Experimental Design) using a cohort retrospective design method. The sample in this study were patients with Gas Gangrene Pedis who were obtained from the patient's medical records in the period January 2021 - March 2022 at Bhayangkara Hospital Kediri with Type II Diabetes Mellitus. Results: Based on the results of the Association Test between Wagner Grade and Gas Therapy, gangrene pedis has a p value of 0.199. The Wagner Grade variable with gas gangrene pedis therapy had an insignificant relationship with debridement measures n = 8 and the most common bacterium was Pseudomonas aeruginosa with n = 4. Patients with gas gangrene pedis who had a history of not routinely controlling because of their DM treatment, there was a high probability of progressive progression. worsening of his condition due to
Sekitar 60%-80% kasus hipertiroidisme diakibatkan oleh Graves’ disease dimana wanita pada usia 20-50th lebih dominan dibandingkan laki-laki. Graves’ disease adalah suatu kelainan autoimun, adanya thyroid stimulating immunoglobulin (TSI), atau bisa disebut dengan thyroid stimulating antibody (TSAb) yang disekresikan di kelenjar tiroid berikatan dengan reseptor thyroid stimulating hormone (TSH) di kelenjar tiroid. Sehingga merangsang kelenjar tiroid untuk bekerja memproduksi hormon tiroksin berdasarkan rangsangan dari reseptor TSH. Rangsangan terus menerus dari TSAb mengakibatkan keadaan hipertiroidisme dan tiromegaly. Keadaan hipertiroidisme menyebabkan denyut jantung melemah dan gambaran pola EKG yang menunjukkan sindrom sinus sakit termasuk bradikardia sinus (denyut jantung <40 bpm), jeda sinus (jeda tiba-tiba nodus sinus lebih pendek dari 2-3 detik), dan henti sinus. Tujuan, Mengetahui karakteristik penderita gangguan kecemasan menyeluruh pada graves disease dengan gambaran EKG sick sinus syndrome (SSS). Metode, Penelitian ini merupakan Systematic Review dengan menggunakan metode Preferred Reporting Items for Systematic Reviews and Meta-analyses atau biasa disebut PRISMA, metode ini dilakukan secara sistematis dengan mengikuti tahapan atau protokol penelitian yang benar. Sumber diambil dari situs PubMed dan situs Google Scholar dengan jurnal terbitan tahun 2017-2022 lalu dilakukan screening didapatkan hasil 15.486. Hasil, Dilakukan klasterisasi jurnal dan didapatkan jumlah jurnal terindex scopus Q1 sejumlah 2 jurnal, Q2 2 jurnal, terindeks Sinta S1 1 jurnal, sehingga terdapat 5 jurnal yang diekstraksi. Kesimpulan, Mayoritas jurnal membahas mengenai usia dan gaya hidup yang berkaitan dengan karakteristik terjadinya grave disease serta faktor risiko grave disease ditentukan berdasarkan usia serta grave disease berhubungan dengan gangguan kecemasan, gambaran EKG sick sinus syndrome (SSS).
Snakebite is a defense mechanism of snakes and can be a medical emergency. Snake venom contains a mixture of protein components that affect the functional activity of the target physiology. The structure of the poison in snake venom has different variations for different snake species. As for snakebite, it can be life-threatening if it has neurotoxic, cytotoxic, or hemotoxic toxic effects. The purpose of this study is to determine the relationship between snakebite incidence to osteomyelitis and cardiogenic shock. The results of this study can be used as a source of information and an objective correlation reference regarding the relationship between snakebite and osteomyelitis and cardiogenic shock. This research is a Systematic Review using the Preferred Reporting Items for Systematic Reviews and Meta-analyses method or commonly called PRISMA, this method is carried out systematically by following the correct research stages or protocols. Antivenom neutralizes toxins in fixed quantities. Both children and adults are given the same amount of antivenom because snakes inject the same amount of poison into both adults and children. Antivenom can be effective as long as the poison is still active in the patient's body causing symptoms of systemic intoxication. It can last for several days or even weeks after the bite. After a series of processes have been passed, based on the results of research in the Scopus-indexed journal on the systematic "The Relationship of Snakebite with Osteomyelitis and Cardiac shock in Pediatric and Adult Patients" a conclusion can be drawn, namely that the majority of journals discuss heart disorders and infections, necrosis of muscles and bones related to poisonous snake bites.
Gas gangrene is a disease that is identical to the incidence of type 2 diabetes mellitus with the characteristics of muscle necrosis / myonecrosis and is a very deadly infection of the inner soft tissues, often caused by gram-positive bacteria such as Staphylococcus aureus, Clostridium perifingens. Diabetes mellitus is a collection of symptoms caused by disturbances in the balance between carbohydrates, fats and proteins caused by absolute or relative insulin deficiency, causing hyperglycemia and glucosuria. to describe the profile of patients with gas gangrene pedis caused by type II diabetes mellitus obtained from the results of secondary data research at Bhayangkara Hospital Kediri Period January 2021 - March 2022. This study is an observational study (Non Experimental Design) using a cohort retrospective design method. The sample in this study were patients with Gas Gangrene Pedis who were obtained from the patient's medical records in the period January 2021 - March 2022 at Bhayangkara Hospital Kediri with Type II Diabetes Mellitus. Results: Based on the results of the Association Test between Wagner Grade and Gas Therapy, gangrene pedis has a p value of 0.199. The Wagner Grade variable with gas gangrene pedis therapy had an insignificant relationship with debridement measures n = 8 and the most common bacterium was Pseudomonas aeruginosa with n = 4. Patients with gas gangrene pedis who had a history of not routinely controlling because of their DM treatment, there was a high probability of progressive progression. worsening of his condition due to
Sekitar 60%-80% kasus hipertiroidisme diakibatkan oleh Graves’ disease dimana wanita pada usia 20-50th lebih dominan dibandingkan laki-laki. Graves’ disease adalah suatu kelainan autoimun, adanya thyroid stimulating immunoglobulin (TSI), atau bisa disebut dengan thyroid stimulating antibody (TSAb) yang disekresikan di kelenjar tiroid berikatan dengan reseptor thyroid stimulating hormone (TSH) di kelenjar tiroid. Sehingga merangsang kelenjar tiroid untuk bekerja memproduksi hormon tiroksin berdasarkan rangsangan dari reseptor TSH. Rangsangan terus menerus dari TSAb mengakibatkan keadaan hipertiroidisme dan tiromegaly. Keadaan hipertiroidisme menyebabkan denyut jantung melemah dan gambaran pola EKG yang menunjukkan sindrom sinus sakit termasuk bradikardia sinus (denyut jantung <40 bpm), jeda sinus (jeda tiba-tiba nodus sinus lebih pendek dari 2-3 detik), dan henti sinus. Tujuan, Mengetahui karakteristik penderita gangguan kecemasan menyeluruh pada graves disease dengan gambaran EKG sick sinus syndrome (SSS). Metode, Penelitian ini merupakan Systematic Review dengan menggunakan metode Preferred Reporting Items for Systematic Reviews and Meta-analyses atau biasa disebut PRISMA, metode ini dilakukan secara sistematis dengan mengikuti tahapan atau protokol penelitian yang benar. Sumber diambil dari situs PubMed dan situs Google Scholar dengan jurnal terbitan tahun 2017-2022 lalu dilakukan screening didapatkan hasil 15.486. Hasil, Dilakukan klasterisasi jurnal dan didapatkan jumlah jurnal terindex scopus Q1 sejumlah 2 jurnal, Q2 2 jurnal, terindeks Sinta S1 1 jurnal, sehingga terdapat 5 jurnal yang diekstraksi. Kesimpulan, Mayoritas jurnal membahas mengenai usia dan gaya hidup yang berkaitan dengan karakteristik terjadinya grave disease serta faktor risiko grave disease ditentukan berdasarkan usia serta grave disease berhubungan dengan gangguan kecemasan, gambaran EKG sick sinus syndrome (SSS).
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