Systematic Review of Nutrient Intake and Growth in Children with Multiple IgE‐Mediated Food Allergies

Sova, C.L.; Feuling, Mary Beth; Baumler, Megan; Gleason, Linda; Tam, Jonathan S.; Zafra, Heidi; Goday, Praveen S.

doi:10.1177/0884533613505870

Cited by 96 publications

(75 citation statements)

References 23 publications

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“…Nevertheless, the study did not evaluate whether body height changes when avoidance of cow's milk is terminated. In another study, multiple food allergies were reported to be associated with decreased growth of body height [17,18,19]. This finding was not seen in our study, which may be because we evaluated more severe patients with more food eliminations than previous studies.…”

Section: Discussioncontrasting

confidence: 56%

Does Terminating the Avoidance of Cow's Milk Lead to Growth in Height?

Yanagida

Minoura

Kitaoka

2015

Int Arch Allergy Immunol

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Background: Cow's milk allergy is known to result in decreased body height; accordingly, the aim of this study was to investigate whether termination of milk avoidance leads to an increase in body height. Methods: Between 2010 and 2011, 253 children with food allergies who were ≥2 years of age visited our outpatient department; 195 had height data available from approximately 1 year after their initial food allergy diagnosis and were included in the study. The height standard deviation scores (HtSDs) were calculated using data from the 2000 Japanese National Physical Growth Survey Report for Infants and Children, and changes in height were then retrospectively evaluated using clinical records. Results: The mean age of the 195 patients was 5.8 ± 3.0 years. The mean HtSDs increased significantly from -0.19 ± 0.99 at diagnosis to -0.12 ± 1.02 (p = 0.025) 1 year later for all children. The HtSDs of 110 cases had increased, but the HtSDs of 85 cases had decreased 1 year after the initial diagnosis. The only significant factor related to increased HtSD was tolerated milk allergy 1 year after the initial diagnosis (p = 0.004). Conclusions: Terminating the avoidance of cow's milk might lead to growth in height, although a prospective study with a larger sample size is needed to confirm these results.

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Section: Discussioncontrasting

confidence: 56%

Does Terminating the Avoidance of Cow's Milk Lead to Growth in Height?

Yanagida

Minoura

Kitaoka

2015

Int Arch Allergy Immunol

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“…Even with close supervision, growth in food-allergic children may lag. 2 While several studies have assessed the relationship of food allergy, nutrition, and growth in smaller groups of children, 2-8 investigation on a population-wide scale is lacking.…”

Section: To the Editormentioning

confidence: 99%

Milk allergy is associated with decreased growth in US children

Robbins

Wood

Keet

2014

Journal of Allergy and Clinical Immunology

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“…Although mortality from food-related anaphylaxis is rare, estimated to be approximately 1.8 per million person-years among foodallergic subjects (5), fear of accidental reactions and social effects of avoidance diets contribute to significantly impaired quality of life for food-allergic children and their caregivers (6). Moreover, avoidance diets can leave food-allergic children at nutritional risk (7). It is estimated that food allergy costs the US almost 25 billion dollars per year in direct and indirect expenses (8).…”

Section: Introductionmentioning

confidence: 99%

Emerging therapies for food allergy

Keet¹,

Wood²

2014

J. Clin. Invest.

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Food allergy is a common condition for which there are currently no approved treatments except avoidance of the allergenic food and treatment of accidental reactions. There are several potential treatments that are under active investigation in animal and human studies, but it is not yet clear what the best approach may be. Here, we review approaches that are currently in clinical trials, including oral, sublingual, and epicutaneous immunotherapy, immunotherapy combined with anti-IgE, and Chinese herbal medicine as well as approaches that are in preclinical or early clinical investigation, including modified protein immunotherapy, adjuvants, DNA vaccines, and helminth administration. We discuss the importance of fully exploring the risks and benefits of any treatment before it is taken to general clinical practice and the need for clarity about the goals of treatment.

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Systematic Review of Nutrient Intake and Growth in Children with Multiple IgE‐Mediated Food Allergies

Cited by 96 publications

References 23 publications

Does Terminating the Avoidance of Cow's Milk Lead to Growth in Height?

Does Terminating the Avoidance of Cow's Milk Lead to Growth in Height?

Milk allergy is associated with decreased growth in US children

Emerging therapies for food allergy

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