Systematic Review for the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Abstract

These members of the evidence review committee are listed alphabetically, and all participated equally in the process. †The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. ‡Former Task Force member; current member during the writing effort. Copies: This document is available on the websites of the American College of Cardiology (www.acc.org) and the American Heart Association (professional.heart.org). A copy of the document is available at http://professional.heart.org/statements by using either "Search for Guidelines & Statements" or the "Browse by Topic" area. To purchase additional reprints, call 843-216-2533 or e-mail kelle.ramsay@wolterskluwer.com.Expert peer review of AHA Scientific Statements is conducted by the AHA Office of Science Operations. For more on AHA statements and guidelines development, visit http://professional.heart.org/statements. Select the "Guidelines & Statements" drop-down menu, then click "Publication Development."Permissions: Multiple copies, modification, alteration, enhancement, and/or distribution of this document are not permitted without the express permission of the American Heart Association. Instructions for obtaining permission are located at http://www.heart.org/HEARTORG/General/Copyright-Permission-Guidelines_UCM_300404_Article.jsp. A link to the "Copyright Permissions Request Form" appears on the right side of the page. With Hypertension .................................................................................................................................. 7 Introduction: Part 1 ............................................................................................................................ 1 ................................................................................................................................. 1 ....................................................................................................................... 1 .................................................................................................................................... ........................................................................................................................ 2 ................................................................................................................................ 2 ................................................................................................................................... ............................................................................................................................. ...................................................................................................................... 33 References ........................................................................................................................................ AbstractObjective: To review the literature systematically and perform meta-analyses to ...

Recommended treatment protocols to improve management of hypertension globally: A statement by Resolve to Save Lives and the World Hypertension League (WHL)

“…The treatment protocols recommended here are based on published clinical trial evidence, guidance from evidence‐based treatment guidelines, implementation experience in large populations, and experiences with in‐country authorities and hypertension experts when selecting country or subnational treatment protocols. According to the recent hypertension treatment guidelines issued by the American College of Cardiology and American Heart Association, 4 medication classes (angiotensin‐converting enzyme inhibitors [ACEI], angiotensin receptor blockers [ARB], calcium channel blockers [CCB], and diuretics) are effective, most patients will require more than 1 medication for control, and single‐pill (fixed dose) combination medications have important advantages . The best scientific evidence suggests that these and other regimens outlined in the WHO HEARTS technical package, all of which use various combinations of the 4 drug classes previously mentioned (with the exception that ACEI and ARB should not be used together in the same individual), can reduce blood pressure and prevent cardiovascular disease in a high proportion of the treated patients.…”

α2δ‐1 couples to NMDA receptors in the hypothalamus to sustain sympathetic vasomotor activity in hypertension

“…Almost half of adults in the USA are considered as having high blood pressure in accordance with new guidelines from the American Heart Association and the American College of Cardiology (Reboussin et al . ). Hypertension is a well‐recognized risk factor for coronary artery disease, kidney failure and stroke.…”

Inhibition of microglial activation in rats attenuates paraventricular nucleus inflammation in Gαi2 protein‐dependent, salt‐sensitive hypertension

“…Hypertension is one of the most significant public health issues in the USA; according to 2017 American Heart Association guidelines, it is estimated that one in two people are hypertensive (Reboussin et al., ). Furthermore, hypertension is the leading cause of chronic kidney disease, stroke and ischaemic heart disease (Lloyd‐Jones et al., ; Mozaffarian et al., ).…”