2006
DOI: 10.1111/j.1365-2036.2006.02809.x
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Systematic review: adherence issues in the treatment of ulcerative colitis

Abstract: SUMMARYUlcerative colitis is a chronic inflammatory and debilitating disease requiring lifelong treatment. First-line therapy for ulcerative colitis is 5-aminosalicylic acid, which suffers from poor patient adherence outside the clinical trial setting.Formulations to deliver 5-aminosalicylic acid to the disease activity site, both orally and topically, are often inconvenient and require multiple daily dosing. Such regimens can interfere with normal life and reduce the overall quality of life, negatively impact… Show more

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Cited by 259 publications
(229 citation statements)
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References 55 publications
(83 reference statements)
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“…One systematic review of research pertaining to the treatment of ulcerative colitis has been published (Kane 2006). This review described non-adherence and dosing/regimen issues as contributing to nonadherence, but it appears that studies in this area did not include any form of electronic monitoring.…”
Section: Other Disordersmentioning
confidence: 99%
“…One systematic review of research pertaining to the treatment of ulcerative colitis has been published (Kane 2006). This review described non-adherence and dosing/regimen issues as contributing to nonadherence, but it appears that studies in this area did not include any form of electronic monitoring.…”
Section: Other Disordersmentioning
confidence: 99%
“…8 Although the terms adherence and compliance are often used interchangeably, 9 adherence is preferred by many health care providers as it implies a cooperative, 2-way relationship versus the 1-way interaction inferred from the term compliance. 10,11 During the roundtable meeting, David T. Rubin noted, "Compliance implies a paternalistic relationship with the physician, whereas adherence suggests more of a patient/physician accommodation or some negotiated relationship."…”
Section: ■■ Defining Adherence and Persistencementioning
confidence: 99%
“…It is important to note however, that this finding could also be the result of older participants having higher standards and more self-demands in regard to their diet, or a better ability to accurately evaluate and report their dietary adherence compared to younger children. Older children are also more likely to have had experience with the disease for a longer period of time, and longer illness duration is one of the factors that have been associated with poorer adherence (for a review see Kane, 2006;López-Sanromán, & Bermejo, 2006). Alternatively, younger children might be more prone to providing socially desirable responses than adolescents.…”
Section: Discussionmentioning
confidence: 99%