A B S T R A C TWe solved the Ornstein-Zernike integral equation to investigate non-linear behavior of osmotic pressure of solutions containing high concentrations of inorganic salts. Net interactions between molecules are assumed to be Lennard-Jones (LJ) potential, and various force fields were used to determine the potential parameters. Relationship between the LJ parameters and permeate flux are discussed, and relative significance of the osmotic pressure and diffusion coefficient on water flux in forward osmosis was investigated.