Syringoma and Mongolism

Butterworth, Thomas

doi:10.1001/archderm.1964.01600050031007

Cited by 76 publications

(45 citation statements)

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“…This was in concordance with the study by Al Aradi et al 4 .However in the study by Bersa et al syringomas were more common in males. Majority of patients with syringoma showed involvement of bilateral lower eye lids which was in concordance with the study by Dr. Butterworth 5 . 17.8% of patients with syringoma had diabetes.…”

Section: Periorbital Miscellaneous Disorderssupporting

confidence: 91%

A Clinical Study of Periorbital Dermatoses

Arjun¹

2017

JMSCR

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Section: Periorbital Miscellaneous Disorderssupporting

confidence: 91%

A Clinical Study of Periorbital Dermatoses

Arjun¹

2017

JMSCR

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“…42 They are round or oval small (0.50-1.5 mm) dermal papules, flesh colored or with a yellow or brown tint. 9,42 They often develop in adolescence, with further lesions developing later in life, and they are twice as common in women. 8,42,43 Plaque-type and eruptive variants have been reported.…”

Section: Syringomamentioning

confidence: 99%

“…9,42 They often develop in adolescence, with further lesions developing later in life, and they are twice as common in women. 8,42,43 Plaque-type and eruptive variants have been reported. 42,43 Syringomas are more common in patients with DS and twice as common in female DS patients.…”

Section: Syringomamentioning

confidence: 99%

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Dermatological Manifestations of Down's Syndrome

Barankin

Guenther

2001

Journal of Cutaneous Medicine and Surgery: Incorporating Medica

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Background: Down's syndrome (DS) is an extensively researched congenital condition characterized by mental retardation and distinct physical features. The cutaneous manifestations of DS are numerous, yet they seldom receive appropriate attention.Objective: To review the dermatological conditions associated with DS.Methods: A review of the medical literature.Results: DS is associated with an increased incidence of numerous dermatological conditions, some of which may be related to an immunological deficiency.Conclusion: Along with the importance of understanding the physical and psychosocial aspects of DS, an appreciation of the dermatological manifestations of this condition is integral to comprehensive medical care.

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“…Syringo mas manifest as small papules with a skin-like or yellowish color, usually located on the eyelids and occasionally on the neck, armpits, genitals or abdomen [1], They have also been defined as 'eruptive hydradenomas' to underline their sudden onset on the trunk and neck [2,3], Palpebral syringomas have been reported frequently in patients with Down's syndrome (DS), with a much higher prevalence compared to that of normal subjects [4][5][6] and, sometimes, in the form of eruptive syringomas with a wide spread aspect [3,7].…”

Section: Introductionmentioning

confidence: 99%

Palpebral Syringomas and Down’s Syndrome

Schepis¹,

Siragusa²,

Palazzo³

et al. 1994

Dermatology

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Background: Palpebral syringomas have been reported to be more frequent in patients with Down’s syndrome than in the normal population. Objective: The aim of the present study was to evaluate, in a population of institutionalized patients with Down’s syndrome, the prevalence of syringomas and their possible cytogenetic relationships. Methods: Sixty-one institutionalized patients with Down’s syndrome were examined in order to assess the presence of palpebral syringomas. Sixty mentally retarded non-Down’s syndrome individuals were used as a control group. Results: Fourteen patients, 13 females and 1 male, were found to be affected. The prevalence of syringomas in both sexes was 23%; 42% of all females, and 55% when only adult females were considered, had syringomas. Thirteen of the 14 affected patients had a karyotype of Down’s syndrome with free trisomy 21, 1 had a mosaicism 47, XX,+21/46, XX. Histologic examination confirmed the diagnosis in all 4 biopsied cases. A clear-cell pattern was observed only in 1 patient while, sporadically, few tubules showed a central syringial-type cuticula. Conclusion: The higher prevalence found in females, as compared to males, can be partially explained by their older age (mean 23.8 vs. 13.9 years). Palpebral syringomas are a common cutaneous pathology in adult females with Down’s syndrome.

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Syringoma and Mongolism

Cited by 76 publications

References 1 publication

A Clinical Study of Periorbital Dermatoses

A Clinical Study of Periorbital Dermatoses

Dermatological Manifestations of Down's Syndrome

Palpebral Syringomas and Down’s Syndrome

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