Syphilitic mucous patches: the resurgence of an old classic

Herrero-González, Josep E.; Amer, Maria Elisabet Parera; Farrés, Marta Ferran; Abelló, Agustí Toll; Barranco, Carles

doi:10.1111/j.1365-4632.2008.03862.x

Cited by 5 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our findings highlight that common oral diseases such as oral candidosis, intraoral human herpes virus infection, hairy leukoplakia, lichen planus, and other conditions considered by others such as lupus erythematosus, erythema multiforme, leukoplakia, erythroleukoplakia, squamous cell carcinoma, and nonspecific erosions should be included in the differential diagnosis of syphilis [ 14 , 15 , 17 , 19 , 24 , 25 , 27 , 31 ].…”

Section: Discussionmentioning

confidence: 85%

Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients

Ramírez‐Amador

Anaya‐Saavedra

Crabtree-Ramírez

et al. 2013

Journal of Sexually Transmitted Diseases

View full text Add to dashboard Cite

Background. Oral lesions may constitute the first clinical manifestation in secondary syphilis, but detailed descriptions in HIV-infected individuals are scarce. Objective. To describe the clinical characteristics of oral secondary syphilis in HIV-infected patients and its relevance in the early diagnosis of syphilis. Methods. Twenty HIV/AIDS adult subjects with oral secondary syphilis lesions presenting at two HIV/AIDS referral centers in Mexico City (2003–2011) are described. An oral examination was performed by specialists in oral pathology and medicine; when possible, a punch biopsy was done, and Warthin-Starry stain and immunohistochemistry were completed. Intraoral herpes virus infection and erythematous candidosis were ruled out by cytological analysis. Diagnosis of oral syphilis was confirmed with positive nontreponemal test (VDRL), and, if possible, fluorescent treponemal antibody test. Results. Twenty male patients (median age 31.5, 21–59 years) with oral secondary syphilis lesions were included. Oral lesions were the first clinical sign of syphilis in 16 (80%) cases. Mucous patch was the most common oral manifestation (17, 85.5%), followed by shallow ulcers (2, 10%) and macular lesions (1, 5%). Conclusions. Due to the recent rise in HIV-syphilis coinfection, dental and medical practitioners should consider secondary syphilis in the differential diagnosis of oral lesions, particularly in HIV-infected patients.

show abstract

Section: Discussionmentioning

confidence: 85%

Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients

Ramírez‐Amador

Anaya‐Saavedra

Crabtree-Ramírez

et al. 2013

Journal of Sexually Transmitted Diseases

View full text Add to dashboard Cite

show abstract

“…Typically, they are multiple, painful, and usually accompanied by other cutaneous or systemic signs that lead to the correct diagnosis. Unusual hypertrophic, serpiginous, and pemphigus-like presentations have also been described [3,7]. In contrast, syphilitic chancre is more rarely located in the oral cavity and appears most commonly over the tongue or hard palate as a solitary painless ulcer without other concomitant manifestations [1,2,3,5].…”

Section: Discussionmentioning

confidence: 99%

Whitish oral lesions in a heavy pipe smoker

Maroñas‐Jiménez

Menis²,

Morales-Raya³

et al. 2015

Dermatology Online Journal

View full text Add to dashboard Cite

Classically known as the "Great Imitator", the diagnosis of syphilis continues to be an enormous challenge. We describe a case of isolated oral lesions as the sole presentation of secondary syphilis and the only clinical clue to previously undiagnosed human immunodeficiency virus infection. The current increase in new cases of syphilis should stimulate physicians to consider this disease in daily practice.

show abstract

“…[ 45 ] One-third of patients with secondary syphilis and the characteristic skin rash present oral manifestations. [ 46 47 48 ]…”

Section: R Esultsmentioning

confidence: 99%

Orofacial bacterial infectious diseases: An update

Irani

2017

J Int Soc Prevent Communit Dent

View full text Add to dashboard Cite

Objectives:Most of the oral infections with odontogenic origin are very common and can be treated by tooth extraction, endodontic therapy, or surgical treatment. Other infectious lesions are the manifestations of systemic diseases such as tuberculosis and syphilis. Skin and underlying subcutaneous tissue, fascia, or muscle is also involved with infectious diseases which range from superficial epidermal infections to very serious necrotizing fasciitis.Materials and Methods:An extensive literature in PubMed, Google Scholar, and Scopus search was performed from 1980 to 2017. All related articles were analyzed.Results:Most oral infections have odontogenic origin. Skin and the underlying subcutaneous tissue, fascia, or muscles are also involved with infectious diseases which range from superficial epidermal infections to very serious necrotizing fasciitis.Conclusions:These facts prove that the interaction between the oral cavity, face skin, and the other organs can risk the people's life. The establishment of a correct diagnosis and recognition of clinical findings are the crucial steps to support and improve professional orofacial health status.

show abstract

Syphilitic mucous patches: the resurgence of an old classic

Cited by 5 publications

References 10 publications

Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients

Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients

Whitish oral lesions in a heavy pipe smoker

Orofacial bacterial infectious diseases: An update

Contact Info

Product

Resources

About