A 53-year-old woman presented with an isolated and nontender necrotic nodule on her left eyelid, which had begun as a small rapid-growing inflammatory papule 3 weeks earlier.Physical examination revealed a 15 mm, erythematous, firm but mobile nodule with a crusted and necrotic core (Fig. 1A). No other cutaneous or mucosal lesions were identified. There was neither regional lymphadenopathy nor systemic involvement and ophthalmological findings were otherwise unremarkable. All laboratory and microbiological studies showed normal or negative results.The patient had a previous 6-month history of disseminated and self-healing crops of similar cutaneous lesions affecting her upper trunk and extremities, which were biopsied months ago (Fig. 1B, C).The eyelid nodule resolved itself spontaneously within 2 weeks. There was no recurrence during the following year. Fig. 1. (A) Isolated erythematous and crusted nodule on the upper left eyelid. (B) The microscopic examination of an incisional skin biopsy found the presence of a diffuse wedge-shaped dermal infiltrate (H&E stain, × 40), (C) containing large atypical lymphocytes within a dense inflammatory background of smaller lymphocytes, histiocytes, neutrophils, and abundant eosinophils (H&E stain, × 200).
Whiplash-shaped acute rash A previously healthy 32-year-old man presented to the emergency room with a persistent, nonpruritic rash on his trunk, which had suddenly appeared 2 days after he ate Chinese food. Physical examination revealed multiple crosslinked linear plaques that appeared like scratches over his chest, back, and shoulders (Figures 1 and 2). He had no dermatographism, and his scalp, nails, palms, and soles were not affected. He had no signs of lymphadenopathy or systemic involvement. Basic blood and urinary laboratory testing, blood cultures, and serologic studies showed normal or negative results. Given the presentation and results of initial testing, his rash was diagnosed as fl agellate erythema,
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