Syphilis, unusual cause of abdominal pain

Navea, César; Mühlenbrock, Christian von; Echeverria, M. G.; Jiménez, Andrea; Poníachik, Jaime

doi:10.1016/j.gastre.2018.11.003

Cited by 1 publication

(1 citation statement)

References 5 publications

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“…Even though physical examinations were performed (revealing genital ulcers in 25% of patients), clinical suspicion of syphilis was only present in 7.8% of cases. However, only a concurrently positive serologic test (reported in 79% of patients) assisted in reaching the correct diagnosis, along with a complete medical (including sexual) history, an accurate physical examination, and a high clinical suspicion [46][47][48][49][50][51][52][53][54][55][56].…”

Section: Discussionmentioning

confidence: 99%

Gastric Syphilis Presenting as a Nodal Inflammatory Pseudotumor Mimicking a Neoplasm: Don’t Forget the Treponema! Case Report and Scoping Review of the Literature of the Last 65 Years

Sinagra

Macaione

Stella

et al. 2023

Gastroenterology Insights

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Despite the fact that gastric syphilis is considered rare, it is reported as a type of organic involvement that is present in a large proportion of secondary syphilis cases, even though gastritis presenting with symptoms is extremely rare. Clinical, radiological, and endoscopic findings are non-specific and frequently mimic the symptoms of gastric adenocarcinoma or lymphoma, making diagnosis difficult. Immunostaining is required for this diagnosis. We would like to emphasize the importance of being suspicious of GS when a gastric mass exhibits the histologic features of an inflammatory pseudotumor (IPT), as previously reported for nodal IPT caused by luetic infection. We described a 56-year-old man who presented to the oncology department with a 3-month history of anorexia, epigastric pain, nausea, vomiting, and weight loss, as well as an initial radiological and endoscopic suspicion of gastric adenocarcinoma, in which immune staining allowed us to diagnose GS. In addition, we conducted an updated scoping review of the scientific literature to show the clinical, laboratory, and therapeutic findings in GS patients over the last 65 years.

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