Syphilis in pregnant women in Zambia.

Ratnam, A. V.; Din, Shahida N.; Hira, Subhash K.; Bhat, Ganapati; Wacha, D.S.O.; Rukmini, A; Mulenga, R C

doi:10.1136/sti.58.6.355

Cited by 45 publications

(42 citation statements)

References 10 publications

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“…Reports from outside Nigeria also show a wide geographical variation. The seroprevalence rate of Treponema pallidum syphilis found in this study is higher than 0.49% found in pregnant Italian women 11 and lower than the 12.5% found in pregnant women in Zambia 7 . It is also lower than the 18.3% found in antenatal care attenders in Mozambique 8 .…”

Section: Introductioncontrasting

confidence: 77%

“…More recently, there has been a resurgence of syphilis 6 . Testing for Treponema pallidum (syphilis) in pregnancy and labour is medically indicated because of the potential risk for congenital infection and foetal loss 7 Treponema pallidum (syphilis) has also acquired a new potential for morbidity and mortality through association with increased risk for HIV infection 6 In women suspected of being at increased risk for syphilis or for populations in which there is a high prevalence of Treponema pallidum (syphilis), additional tests should be performed during the third trimester at twenty-eight weeks and again at delivery. Seropositive women should be considered infected and should be treated unless prior treatment with fall in antibody titre is medically documented.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Serodynamics Of Treponema Pallidum In Serum Of Pregnant Women In Benin City

Ibadin¹,

Enabulele²,

Eghafona³

et al. 2009

bjpm

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Section: Introductioncontrasting

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Serodynamics Of Treponema Pallidum In Serum Of Pregnant Women In Benin City

Ibadin¹,

Enabulele²,

Eghafona³

et al. 2009

bjpm

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“…79 Syphilis is particularly common in Africa, with prevalence estimates around 10%. [313][314][315] Syphilis is also recognized as a major contributor to perinatal and infant mortality in the African region. 311,[315][316][317] In Ethiopia, ϳ6% of perinatal mortality was due to syphilis.…”

Section: Syphilis Screening and Treatmentmentioning

confidence: 99%

Community-Based Interventions for Improving Perinatal and Neonatal Health Outcomes in Developing Countries: A Review of the Evidence

et al. 2005

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ABSTRACT. Background. Infant and under-5 childhood mortality rates in developing countries have declined significantly in the past 2 to 3 decades. However, 2 critical indicators, maternal and newborn mortality, have hardly changed. World leaders at the United Nations Millennium Summit in September 2000 agreed on a critical goal to reduce deaths of children <5 years by two thirds, but this may be unattainable without halving newborn deaths, which now comprise 40% of all under-5 deaths. Greater emphasis on wide-scale implementation of proven, cost-effective measures is required to save women's and newborns' lives. Approximately 99% of neonatal deaths take place in developing countries, mostly in homes and communities. A comprehensive review of the evidence base for impact of interventions on neonatal health and survival in developingcountry communities has not been reported.Objective. This review of community-based antenatal, intrapartum, and postnatal intervention trials in developing countries aimed to identify (1) key behaviors and interventions for which the weight of evidence is sufficient to recommend their inclusion in communitybased neonatal care programs and (2) key gaps in knowledge and priority areas for future research and program learning.Methods. Available published and unpublished data on the impact of community-based strategies and interventions on perinatal and neonatal health status outcomes were reviewed. Evidence was summarized systematically and categorized into 4 levels of evidence based on study size, location, design, and reported impact, particularly on perinatal or neonatal mortality. The evidence was placed in the context of biological plausibility of the intervention; evidence from relevant developed-country studies; health care program experience in implementation; and recommendations from the World Health Organization and other leading agencies.Results. A paucity of community-based data was found from developing-country studies on health status impact for many interventions currently being considered for inclusion in neonatal health programs. However, review of the evidence and consideration of the broader context of knowledge, experience, and recommendations regarding these interventions enabled us to categorize them according to the strength of the evidence base and confidence regarding their inclusion now in programs. This article identifies a package of priority interventions to include in programs and formulates research priorities for advancing the state of the art in neonatal health care.Conclusions. This review emphasizes some new findings while recommending an integrated approach to safe motherhood and newborn health. The results of this study provide a foundation for policies and programs related to maternal and newborn health and emphasizes the importance of health systems research and evaluation of interventions. The review offers compelling support for using research to identify the most effective measures to save newborn lives. It also may facilitate dialogue with policy...

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“…A contemporary study to this found that syphilis was the fourth most common cause of perinatal death and accounted for 10% of the 70 perinatal deaths per 1000 births and almost five per cent of all postnatal deaths (7). Rates for congenital syphilis have been reported to be 850/100,000 livebirth in Lusaka and 3,200/100,000 in Addis Ababa (8).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of syphilis in pregnancy in Addis Ababa

Kebede¹,

Chamiso²

2009

E Af Med Jrnl

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Objective: To assess the extent of syphilis seropositivity in pregnant women, identify the risk factors associated with it and re-evaluate the need for routine antenatal care screening for syphilis. Design: Prospective cross-sectional study. Setting: Three teaching hospitals of Addis Ababa University Faculty of Medicine, Department of Obstetrics and Gynecology, Addis Ababa, Ethiopia. Subjects: A total of 410 pregnant women attending antenatal care from April 1997 to September 1997 were included in the study. Subjects were excluded from the study if they were registered prior to the study period. Main outcome measures: Seropositivity for syphilis, and socio-demographic factors related to it. Results: Among the study population, twelve women (2.9%) were positive for Venereal Disease Research Laboratory (VDRL). The study showed that the seropositive women were more likely to be those with lesser income (<600 birr/month). Past history of abortion was significantly associated with VDRL seropositivity (p<0.05). Similarities and differences between the findings of this study and other national and international reports have been noted. Conclusion: It is necessary to conduct a large scale study to evaluate if screening is costeffective and establish risk scoring methods.

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Syphilis in pregnant women in Zambia.

Cited by 45 publications

References 10 publications

Serodynamics Of Treponema Pallidum In Serum Of Pregnant Women In Benin City

Serodynamics Of Treponema Pallidum In Serum Of Pregnant Women In Benin City

Community-Based Interventions for Improving Perinatal and Neonatal Health Outcomes in Developing Countries: A Review of the Evidence

Prevalence of syphilis in pregnancy in Addis Ababa

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