Syphilis Among Newly Diagnosed Therapy-Naive HIV Patients in Belém, Pará, Amazon Region of Brazil

Neto, Pedro Leão Fontes; Fernandes, Érika M F; Nascimento, Matheus R O do; Paes, Rafaella P; Irias, Susan D Flores; Avelino, Maria E.S.; Torres, Maria Karoliny da Silva; Azevedo, Vânia Nakauth; Feitosa, Rosimar Neris Martins; Oliveira-Filho, Aldemir Branco; Vallinoto, Antônio Carlos Rosário; Machado, Luiz Fernando Almeida

doi:10.1089/aid.2019.0007

Cited by 4 publications

(6 citation statements)

References 4 publications

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“…Several factors (study design, sampling, laboratory tests and potentially temporal/local factors) may be interfering with these differences in the prevalence of syphilis. A comparison restricted to the city of Belém (Brazilian state of Pará) indicates that the prevalence of syphilis detected in this study is lower than the records made in two studies: newly diagnosed HIV therapy patients (17.3%) ( 19 ), and HIV/AIDS patients receiving care at the URE-DIPE from 2007 to 2008 (7.3%) ( 20 ). On the other hand, the number of PLWHA with higher titrations (1:128; 1:256; 1:512) using VDRL is higher in this study compared to that observed in the years 2007 and 2008 ( 20 ).…”

Section: Discussioncontrasting

confidence: 60%

“…Age up to 30 years (young adults) was identified as the main risk factor for syphilis in PLWHA in the city of Belém, despite the predominance of people over 40 years in the sample. This fact had not yet been observed in studies conducted in Brazil (11,19,20). It is an alert to the health authorities of the state of Pará and northern Brazil, because it is an indication that the methods of prevention of STIs are not being used adequately in the age group of beginning and, likely, of greater sexual activity.…”

Section: Discussionmentioning

confidence: 77%

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Prevalence and Factors Associated With Syphilis in People Living With HIV/AIDS in the State of Pará, Northern Brazil

Neto

Fonseca

Avelino

et al. 2021

Front. Public Health

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Syphilis continues to be a public health problem worldwide and its incidence has increased in people living with HIV/AIDS in recent years. This study determined the prevalence and factors associated with syphilis in people living with HIV/AIDS in the city of Belém, northern Brazil. A cross-sectional study was conducted from June to November 2018. A total of 500 people living with HIV/AIDS attended at a specialized unit of the public health network of the State of Pará were studied. Questionnaires were used to collect socio-demographic data and potential risk factors for syphilis. Blood samples were collected from all subjects and screened for syphilis using VDRL, and the seropositive were confirmed using FTA-abs. Logistic regressions were used to identify the factors associated with syphilis. Most subjects were male (56.8%), had more than 40 years (54.0%), single (63.0%), had finished high school (54.2%), had monthly income ≤1 minimum wage (72.4%), and had been born to the city of Belém (59.8%). Prevalence of syphilis was 6.4%. Eight characteristics/behaviors associated with syphilis: male, young adults, single, studied at least high school, monthly income >1 minimum wage, homosexual/bisexual, does not use or sporadically use condoms during sexual intercourse, and have had more than one sexual partner in the last three months. The prevalence of syphilis in people living with HIV/AIDS in Belém is low when compared to other Brazilian states. However, there is a need for public policies and actions to monitor, control and prevent these two sexually transmitted infections.

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Section: Discussioncontrasting

confidence: 60%

Section: Discussionmentioning

confidence: 77%

Prevalence and Factors Associated With Syphilis in People Living With HIV/AIDS in the State of Pará, Northern Brazil

Neto

Fonseca

Avelino

et al. 2021

Front. Public Health

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“…A high prevalence of HBV co-infection among HIV-1 carriers was observed in the state of Piauí, with the identification of genotypes A, F and D [ 51 ] and a low prevalence of hepatitis C virus (HCV) in Belém, Pará [ 52 ]. HPV was detected in small proportion (26.8%), with the predominance of types of low oncogenic risk and a positive correlation with the decrease in the amount of CD4 + T lymphocytes in HIV-1 patients in Belém, Pará [ 53 ], but anti- C. trachomatis and anti- C. pneumoniae antibodies [ 54 ] and syphilis [ 55 ] were detected at high levels of infection. The investigations presented demonstrate the spread of other STIs among a population group who should be more cautious and oriented to avoid infections which can further compromise their immunological response and boost the inflammatory damage.…”

Section: The Impact Of Hiv-1 In the Brazilian Amazon: From Description To Current Timesmentioning

confidence: 99%

“…The greatest importance of this study was in the investigation of a population group that should already be looking for basic preventive measures to avoid the transmission of other STIs. In another study with HIV-1 carriers, who were ART naive, the prevalence of T. pallidum was 17.3% [ 55 ].…”

Section: The Not Yet Defined Impact Of Treponema Pallidum In the Brazilian Amazonmentioning

confidence: 99%

The Epidemiological Impact of STIs among General and Vulnerable Populations of the Amazon Region of Brazil: 30 years of Surveillance

Machado

Fonseca

Queiroz

et al. 2021

Viruses

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Sexually transmitted infections (STIs) represent a worldwide public health problem and, although many of them are curable, they continue to be neglected, especially in areas with a low human development index, such as in the northern region of Brazil. This review describes the results of 30 years of studies at the Virus Laboratory at the Federal University of Pará, including the prevalence and molecular epidemiology of HIV-1, HTLV-1/2, HPV, HBV, Treponema pallidum and Chlamydia trachomatis among urban and non-urban populations, and also in vulnerable groups in the Brazilian Amazon. Control strategies and challenges in preventing STIs are discussed considering this immense geographic region, where essential health services are unable to reach the entire population, especially the most vulnerable, such as female sex workers, people who use illicit drugs, remnants of quilombolos and indigenous communities.

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“…Fatores associados a um maior risco de sífilis incluem início da atividade sexual antes dos 14 anos; práticas sexuais com múltiplos parceiros; recebimento de presentes, drogas ou outros incentivos em troca de sexo; infecção por HIV e história prévia de sintomatologia de infecção sexualmente transmissível (30,(33)(34)(35)(36)(37)(38)(39). Dentre as PVHIV, a prevalência de sífilis em diferentes regiões do Brasil variou de 6 a 51% em diferentes estudos (36)(37)(38)(40)(41)(42)(43).…”

Section: Segundo Relatório Publicado Pelo Centers For Disease Control...unclassified

Impacto da coleta de líquido cefalorraquidiano para investigação de neurossífilis em pessoas vivendo com HIV sem sintomas neurológicos: um estudo de coorte

Henriques¹

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Syphilis Among Newly Diagnosed Therapy-Naive HIV Patients in Belém, Pará, Amazon Region of Brazil

Cited by 4 publications

References 4 publications

Prevalence and Factors Associated With Syphilis in People Living With HIV/AIDS in the State of Pará, Northern Brazil

Prevalence and Factors Associated With Syphilis in People Living With HIV/AIDS in the State of Pará, Northern Brazil

The Epidemiological Impact of STIs among General and Vulnerable Populations of the Amazon Region of Brazil: 30 years of Surveillance

Impacto da coleta de líquido cefalorraquidiano para investigação de neurossífilis em pessoas vivendo com HIV sem sintomas neurológicos: um estudo de coorte

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