Synthesis, Structural Characterization, and Preliminary Biological Characterization of Organotin Polyethers Derived from Hydroquinone and Substituted Hydroquinones

Organo-tin antitumor compounds: Their present status in drug development and future perspectives

“…Further, compounds derived from known antibacterial agents show the ability to inhibit bacteria, cancer cell lines, and viral replication contributing to the ongoing increase in data that demonstrates the common cellular pathways are utilized during tumor growth and bacterial/viral infections [61][62][63][64][65][66][67]. Roner et al have reported a wide variety of tin-containing polymers exhibiting antiviral activity to investigate the correlation between structure and inhibition of cancer cell lines [68][69][70][71][72][73][74]. It was demonstrated that organotin polymers exhibit viral reduction specific to the nature of the organotin and Lewis base nucleophiles.…”

“…Recent focus has been on investigating organotincontaining polymers for inhibition of pancreatic cancers. Only the organotin polymers exhibited decent inhibition of the pancreatic cancer cells [68,[104][105][106].…”

Control of Prostate Cancer Using Organotin Polymers

“…Yield and molecular weight data for the dibutyltin polyethers derived from hydroquinone and the hydroquinone derivatives[54] …”

Synthesis of organoarsenic, organoantimony, and organobismuth poly(ether esters) from reaction with glycyrrhetinic acid and their preliminary activity against pancreatic cancer cell lines

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14]69,70] Bridging asymmetric carbonyl absorptions are found around 1570. The bridging symmetric carbonyl band is found around 1410-1430.…”

“…Included in the metal atoms incorporated into polymers are tin, [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Group IVB metallocenes, [19][20][21][22][23][24][25][26][27][28][29][30] platinum, [31,32] and Group VA metals, namely arsenic, antimony, and bismuth. [33][34][35][36][37][38][39][40] Much of the most recent effort has focused on the special properties that can be incorporated into such polymers because of the presence of the metal moiety.…”