SYNTHESIS, SPECTROSCOPIC, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF Pd(II) COMPLEXES CONTAINING TRIDENTATE SCHIFF BASES

Demehin, Abidemi Iyewumi; Oladipo, Mary Adelaide; Semire, Banjo

doi:10.21608/ejchem.2019.12319.1766

Cited by 5 publications

(11 citation statements)

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“…The aromatic protons appeared as multiplets at δ 7.70-6.90 ppm [15,30,31,35]. A sharp singlet signal assigned to the protons of methoxy and methyl groups appeared at δ 3.81 and 2.20 ppm in the spectra of compounds I and III respectively [11,[35][36][37]. The 13 C NMR spectra of the compounds were consistent with the 1 H NMR.…”

Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 64%

“…The TAC studies were performed three times and the mean was expressed as equivalents of ascorbic acid [22] 13 The 1 H NMR spectra of the salicylaldimines displayed a singlet signal at δ 13.90-12.70 ppm which was attributed to the phenolic -OH protons [18,27,[29][30][31][32][33]. All the salicylaldimines displayed a singlet signal at δ 8.91-8.85 ppm assigned to the azomethine (−HC=N) protons [15,27,30,31,[33][34][35][36] which further confirmed the formation of the salicylaldimines. The aromatic protons appeared as multiplets at δ 7.70-6.90 ppm [15,30,31,35].…”

Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 99%

“…The spectra displayed the azomethine carbon peaks in the range 163.25-161.75 ppm and the aromatic carbons around 160.12-112.80 ppm. The spectra of compounds I and III displayed the carbons of the methoxy and methyl groups at δ 56.31 and 17.73 ppm respectively [11,15,27,33,[35][36][37]. The UV spectra of the compounds displayed two absorption peaks around 286-262 and 351-360 nm which were attributed to n-π* of the azomethines and π-π*of the aromatic rings in the compounds.…”

Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 99%

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DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

Demehin¹

2021

JSRR

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Three substituted monodentate salicylaldimines namely 5-chloro-N-[(2- methoxy) phenyl] salicylaldimine [I], 5-chloro-N-[(4-chloro)phenyl]salicylaldimine [II] and 5-chloro-N-[(2-methyl-5-chloro)phenyl] salicylaldimine [III] were synthesized and characterized by elemental analysis, IR, UV, 1H and 13C NMR. Theoretical calculations were also performed on the optimized structures of the compounds. The IR, NMR and UV spectra of the compounds were calculated and the results compared with the corresponding experimental spectra to augment the structural elucidation. The calculated IR, NMR and UV values were in agreement with the experimental results. The total antioxidant capacities of the compounds were determined by phosphomolybdenum assay.

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Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 64%

Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 99%

Section: Phosphomolybdate Total Antioxidant Capacity Assaymentioning

confidence: 99%

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DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

Demehin¹

2021

JSRR

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“…1-3) revealed a singlet signal at δ 13.00-12.33 ppm assigned to the phenolic -OH protons. All the compounds showed a singlet signal at δ 8.91-8.85 ppm attributed to the azomethine (−HC=N) protons which further confirmed the formation of the Schiff bases [18,24,25,27]. The aromatic protons appeared as multiplets at δ 7.40-6.70 ppm [18,[26][27][28].…”

Section: Characterization Of the Schiff Basesmentioning

confidence: 83%

“…The IR spectra results of the compounds confirmed the formation of the azomethine bonds ⱱ(−HC=N). All the compounds exhibited the azomethine absorption bands in the range 1617-1614 cm The compounds showed the aromatic (C=C) bands in the range 1591-1447 cm -1 [18,[24][25][26][27][28].…”

Section: Characterization Of the Schiff Basesmentioning

confidence: 99%

Computational Modelling and Antioxidant Activities of Substituted N-(Methoxysalicylidene) Anilines

Demehin¹

2021

CSIJ

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The computational modelling and total antioxidants activities of three N-(methoxysalicylidene) anilines namely N- (methoxysalicylidene)aniline [I], N-(methoxysalicylidene)-4-chloroaniline [II] and N-(methoxysalicylidene)-5-chloro-2-methylaniline [III] were reported. The compounds were synthesized and characterized by elemental analysis, infrared, ultraviolet, proton and carbon-13 nuclear magnetic resonance. Quantum chemical computations were also performed on the optimized structures of the compounds using Density Functional Theory. The infrared, nuclear magnetic resonance and ultraviolet spectra of the compounds were calculated and the results likened to the equivalent experimental spectra to enhance the structural identification. The calculated infrared, nuclear magnetic resonance and ultraviolet spectra were comparable to the experimental spectra. The total antioxidant capacities of the Schiff bases were evaluated by phosphomolybdenum assay and the results indicated that all the synthesized compounds displayed antioxidant activities.

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Novel Schiff Bases Ligands and Their Complexes: Thermal Analysis, Antibacterial Activity, and Molecular Docking

et al. 2021

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The transition metal complexes of novel tetradentate-ketoenamine ligands were synthesised by condensing β-diketone (acetylacetone, 3-chloro acetylacetone) with 4,4'-methylenedianiline. Fourier-transform infrared (FTIR) spectroscopy, proton nuclear magnetic resonance ( 1 H NMR) spectroscopy, carbon-13 NMR ( 13 C NMR) spectroscopy, electron ionisation mass spectrometry (EIMS), elemental analysis, and UV-visible (UV-Vis) spectroscopy were used to describe the compounds while thermogravimetric (TG/DTG) analysis was used to investigate the thermal breakdown of the complexes. All of the complexes showed outstanding stability as well as different degrees of thermal decomposition. Antibacterial activity was tested using gram-positive (Bacillus subtilis, Staphylococcus aureus) and gram-negative (Bacillus subtilis, Staphylococcus aureus) bacteria (Escherichia coli, Salmonella typhi). Minimal inhibitory concentrations (MICs) of 0.5 to 2 mM/ml and minimum bacterial concentrations (MBCs) of 2 to 4 mM/ml were used in this study. A molecular docking study was also conducted to ensure that the compounds connected well to the active sites of the target enzymes; such as topoisomerase II DNA gyrase enzymes (2XCT) and methicillin-resistant Staphylococcus aureus (MRSA,2x3f.pdb).

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SYNTHESIS, SPECTROSCOPIC, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF Pd(II) COMPLEXES CONTAINING TRIDENTATE SCHIFF BASES

Cited by 5 publications

References 0 publications

DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

DFT Calculations and Total Antioxidant Capacity Studies of some Substituted Monodentate Salicylaldimines

Computational Modelling and Antioxidant Activities of Substituted N-(Methoxysalicylidene) Anilines

Novel Schiff Bases Ligands and Their Complexes: Thermal Analysis, Antibacterial Activity, and Molecular Docking

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