Synthesis, spectroscopic and voltammetric studies of a novel Schiff-base of cysteine and saccharin

Çakır, Semiha; Odabaşoğlu, Mustafa; Bíçer, Ender; Yazar, Zehra

doi:10.1016/j.molstruc.2008.07.015

Cited by 7 publications

(2 citation statements)

References 48 publications

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“…The asymmetric and symmetric stretching vibrations of the SO 2 group in the FTIR spectrum of saccharin have already been reported at 1337 and 1179 cm -1 , respectively [52]. Another characteristic IR absorption for A B C saccharin is S-N-C which appears at 975 cm -1 [25] (Fig. 5).…”

Section: Spectrophotometric Measurementsmentioning

confidence: 78%

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Synthesis, spectroscopic and electrochemical characteristics of a novel Schiff-base from saccharin and tryptophan

Çakır

Bíçer

2010

JICS

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In the present work, a novel Schiff-base was synthesized by the reaction of saccharin with tryptophan and characterized by elemental analysis as well as UV-Vis, FT-IR, 1 H NMR spectroscopic data. The voltammetric behavior of Schiff-base was also studied on the hanging mercury drop electrode (HMDE) by using Square-Wave Voltammetry (SWV) and Cyclic Voltammetry (CV) techniques. The voltammograms of the Schiff-base exhibited two irreversible reduction peaks in Britton-Robinson buffer (pH 7.0-10.0) for the potential range from 0.0 V to -1.4 V. These peaks which appeared at more positive potentials than the reduction peaks of tryptophan and saccharin, may be assigned to the cathodic reductions of C-N + and >C=N-moieties of Schiffbase.

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Section: Spectrophotometric Measurementsmentioning

confidence: 78%

“…However, a novel Schiff-base of cysteine and saccharin has been recently synthesized and characterized by ÇakÕr et al [25]. Yet, nothing new on the interaction mechanism of saccharin with tryptophan is reported.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, spectroscopic and electrochemical characteristics of a novel Schiff-base from saccharin and tryptophan

Çakır

Bíçer

2010

JICS

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Synthesis, Characterization, and Antibacterial Activity of Co(II), Ni(II), and Pd(II) Complexes with Bisdithiocarbamate and Cyclic Amines Ligands

Mohammed

Mustafa

Aziz

2022

Macromolecular Symposia

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Reaction of metal saltsCoCl 2 •6H 2 O,NiCl 2 •6H 2 O and Na 2 [PdCl 4 ] with thymine bisdithiocarbamate and uracil bisthiocarbamate in molar ratio 2:1 (metal/ligand) affords the presumably tetrahedral complexes [M 2 (dtc)(H 2 O) 4 Cl 2 ] M; Co, Ni and square planer complexes [Pd(dtc)(H 2 O) 4 Cl 2 ] dtc=tdtc, utdc. Dithiocarbamates (dtcs) behave as monodentate ligands. Reaction of [M 2 dtc (H 2 O) 4 Cl 2 ] M; Co (II), Ni (II), and Pd(II) with 1,10-Phen.″ or 2,2′-BiPy. (two equivalents) affords tetrahedral complexes of type [M 2 dtc(Amin) 2 Cl 2 ] M; Co, Ni and square planer complexes [Pd 2 dtc(Amin) 2 Cl 2 ], bis(dithiocarbametes) acts as a monodentate ligand and binds to the metal center through the soft sulfur atoms. Antibacterial activity of ligands and complexes is evaluated with two types of bacteria Staphylococcus aurous (gram-positive) and Escherichia coli (gram-negative). The complexes are characterized by physico-chemical and spectroscopic methods.

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A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα

Sandhaus

Taylor

Edwards

et al. 2016

Inorganic Chemistry Communications

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A novel complex, [Cu(acetylethTSC)Cl]Cl•0.25C2H5OH 1 (where acetylethTSC = (E)-N-ethyl-2-[1-(thiazol-2-yl)ethylidene]hydrazinecarbothioamide), was shown to have anti-proliferative activity against various colon and aggressive breast cancer cell lines. In vitro studies showed that complex 1 acted as a poison inhibitor of human topoisomerase IIα, which may account for the observed anti-cancer effects.

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Synthesis, spectroscopic and voltammetric studies of a novel Schiff-base of cysteine and saccharin

Cited by 7 publications

References 48 publications

Synthesis, spectroscopic and electrochemical characteristics of a novel Schiff-base from saccharin and tryptophan

Synthesis, spectroscopic and electrochemical characteristics of a novel Schiff-base from saccharin and tryptophan

Synthesis, Characterization, and Antibacterial Activity of Co(II), Ni(II), and Pd(II) Complexes with Bisdithiocarbamate and Cyclic Amines Ligands

A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα

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