Synthesis, Spectral, Thermal and Biological Studies of Mn(II), Co(II), Ni(II) and Cu(II) Complexes with 1‐(((5‐Mercapto‐1H‐1,2,4‐triazol‐3‐yl)imino)‐methyl)naphthalene‐2‐ol

Abstract

Mn(II), Co(II), Ni(II) and Cu(II) complexes of 5‐mercapto‐1,2,4‐triazol‐3‐imine‐2′‐hydroxynaphthaline have been synthesized and characterized by elemental analysis, IR, 1H NMR, EI‐mass, UV‐Vis, and ESR (electron spin resonance) spectra, molar conductance, magnetic moment measurements, DC conductivity and thermogravimetric analysis. IR spectra confirm that the ligand molecule existed in both thione and thiole forms. The molar conductance values indicate the complexes are nonelectrolyte. The magnetic moment values of the complexes display paramagnetic behavior. All studies confirm the formation of an octahedral geometry for complex 1 and the other complexes have tetrahedral geometrical structures. The structures of the complexes have also been theoretically studied by using the molecular mechanic calculations by the hyperchem. 8.03 molecular modeling program which confirm the proposed structures. The Schiff‐base ligand and its metal complexes have also been screened for their antimicrobial activities.

Synthesis, spectral, antitumor, antioxidant and antimicrobial studies on Cu(II), Ni(II) and Co(II) complexes of 4-[(1H-Benzoimidazol-2-ylimino)-methyl]-benzene-1,3-diol

“…Metal complexes of Schiff base compounds are a class of important compounds in medicinal and pharmaceutical field. They have wide applications in some biological aspects [26,[28][29][30][31][32][33] The present work aims to synthesize a new Schiff base ligand namely, 4-[(1H-Benzoimidazol-2-ylimino)-methyl]-benzene-1,3-diol and its complexes with Co(II), Ni(II) and Cu(II) ions. The complexes have been characterized by several tools of analyses such as elemental analyses, magnetic moment measurements, , ICP , molar conductance, ESR, IR, UV-Vis spectra.…”

“…Schiff bases are used extensively as ligands in coordination chemistry. In view of their interesting structural properties and wide ranging uses, studies of the Schiff base complexes have attracted the attention of many investigators [22][23][24][25][26][27]. Metal complexes of Schiff base compounds are a class of important compounds in medicinal and pharmaceutical field.…”

Cu(II) Complexes of 4-[(1E)-N-{2-[(Z)-Benzylidene-amino]ethyl}ethanimidoyl]benzene-1,3-diol Schiff Base: Synthesis, Spectroscopic, In-Vitro Antioxidant, Antifungal and Antibacterial Studies

“…2-Hydroxy-1-(4-hydroxyphenyl)ethenone Schiff bases are of particular interest due to their wide range of biological activities, as shown by 4-[(1 E )- N -(2-aminoethyl)ethanimidoyl]benzene-1,3-diol [ 9 ], and antioxidant and antibacterial activities exemplified by derivatives of 1-phenylbutan-1-one Schiff base [ 10 ]. Other activity includes structural activity demonstrated by octahedral and tetrahedral complexes of naphthalene-2-ol derivative [ 11 ]. Cu(II) complexes of the Schiff base (7 E )-7-(3-ethoxy-2-hydroxybenzylideneamino)-4-methylquinolin-2(1 H )-one were reported as a potential therapeutic agent [ 12 ].…”

Study of the thermal behavior in solid state of Mn(II)-Diclofenac Complex

“…The studies of the stable metal complex can be used for different purposes, such as the obtaining metallic oxides to advanced materials (ceramics, glasses, among others) or to obtain new properties of application in biological functions [1][2][3][4] . Thus, the thermogravimetry is a valuable technique for studying the thermal behavior of solid-state compounds of metal complexes, which are essential to synthesize complexes in the desired stoichiometry in several applications.…”