Synthesis, spectral characterization, solution equilibria, in vitro antibacterial and cytotoxic activities of Cu(II), Ni(II), Mn(II), Co(II) and Zn(II) complexes with Schiff base derived from 5-bromosalicylaldehyde and 2-aminomethylthiophene

Physicochemical studies and biological activity of mixed ligand complexes involving bivalent transition metals with a novel Schiff base and glycine as a representative amino acid

“…The condensation of 5-bromosalicylaldehyde with 2-amino methylthiophene in boiling ethanol yields a Schiff base compound (ATS) as reported in literature [31]. The elemental analyses for the interaction of Schiff base ligand and glycine amino acid with metal (II) chloride in EtOH agree well with a 1:1:1 M(II):ATS:Gly stoichiometry for all the complexes.…”

“…The Schiff base was prepared as reported in literature [31] by mixing an ethanolic solution (20 mL) of 2.01 g (0.01 mol) of 5-bromosalicylaldehyde with 1.13 g (0.01 mol) of 2-amino methylthiophene in the same volume of ethanol. The mixture then refluxed with stirring for 1 hour.…”

Crystal Structure and Characterization of a New Eight Coordinated Cadmium Complex

“…5,6 Schiff bases show strong complexing ability towards some toxic metals 7 and diverse biological activities, such as antibacterial and antitumor. 8,9 In this work the preparation and characterization of the cadmium(II) complex, [Cd(L)(CH 3 COO) 2 ].2H 2 O (1) with N,N'-bis(2-pyridinecarboxalidene)-1,2-cyclohexanediamine (L, Scheme 1) is described.…”

Synthesis, Characterization, Spectral Studies, Antibacterial Evaluation, Thermodynamics and DFT Calculations of Dimethyltin(IV) Dichloride Schiff Base

“…In the complexes, this band is shifted to the 1238-1275 cm -1 upon complexation with the metal which can be attributed to the coordination of the carbonyl oxygen to the metal tin(IV) center. 6,39,40 New band appearing in the complexes in the low frequency ranges 423-480 cm -1 is due to the ν Sn-O vibrations and thus confirm the bonding of oxygen to the tin atom as shown in Scheme 1. H NMR spectra of all the complexes were recorded in DMSO-d 6 solvent and the data along with assignments are listed in the experimental section.…”

“…1,2 This compounds with strong donor atom are excellent in catalysis and biological replication due to their strong coordination abilities with metal ions. 3 There are several reports on metal complexes such as Ni(II), Cu(II), Co(II) and Sn(IV) of the Schiff base ligands that have a variety of applications including biochemical reactions and biological regulators, 4,5 clinical, 6,7 analytical 8,9 and industrial uses in addition to their important roles in enhancing the solubility and stability of homogeneous or heterogeneous catalysts. [10][11][12] Over the years, much effort has done on coordination of Schiff bases to organotin(IV) compounds.…”