Synthesis, Characterization, Spectral Studies, Antibacterial Evaluation, Thermodynamics and DFT Calculations of Dimethyltin(IV) Dichloride Schiff Base

Abstract

Sn NMR, IR and mass spectroscopy. IR spectral data show that the fifth coordination position of tin atom is occupied by an oxygen atom of Schiff base ligands. In the light of titled techniques, trigonal bipyramidal geometry around the tin atom is proposed for the synthesized complexes. The in vitro antibacterial activities of the complexes against Staphylococcus aureus and Escherichia Coli have been studied. It was found that they possess significant antibacterial activity. Also, DFT/B3LYP method was used to analyze the electronic structures and study of the geometries. The thermodynamic formation constants of the complexes were determined spectrophotometrically at 25 °C in DMF solvent.

EVALUATION OF In-vitro ANTIBACTERIAL ACTIVITY AGAINST GRAM-NEGATIVE BACTERIA USING SILVER NANOPARTICLES SYNTHESIZED FROM Dypsis lutescens LEAF EXTRACT

“…A very good spectrum of antibacterial activity was found in the sample against both bacteria. Antibacterial activity is most likely derived from electrostatic attention between the negative charged microorganism cell membrane and positively charged NPs (Esmaielzadeh et al, 2015;Mushir et al, 2016).…”

Tin(IV) Schiff base complexes: Synthesis, thermodynamic and anti bacterial investigation, experimental and theoretical studies

“…Schiff base ligands containing hetero atoms such as N, O, and S show a broad biological activity and are of special interest because of their variety of ways in which they are interacted to metal ions. Schiff base in neutral and deprotonated forms react with organotin(IV) halides and the complexes extensively studied because they have some characteristics properties like manifestations of novel structures, thermal stability, high synthesis flexibility, medicinal utility, industrial applications and relevant biological properties [9][10][11][12]. In addition to their special antimicrobial activities, organotin(IV) compound with Schiff bases present an interesting variety of structural possibilities, so that a remarkable diversity in structure may be observed even when only a small change in the chemistry occurs [13].…”