Synthesis, photophysical, and electrochemical properties of 2,5-diaryl-indolizines

Synthesis and photophysical properties of 1,2‐diphenylindolizine derivatives: fluorescent blue‐emitting materials for organic light‐emitting device

“…The synthetic routes for compounds 1–5 are outlined in Scheme . The design idea to these compounds was straightforward: 1,2‐diphenylindolizine backbone was derived with various modifying groups and the derivatization can be easily realized by microwave‐assisted Suzuki coupling reaction. The synthesis could be generalized into three steps.…”

“…Recently, indolizines, 10 π‐electron aromatic N ‐heterocyclic compounds, have been reported for use as luminescent materials such as for optoelectronic devices , dyes , sensors and probes , Indolizines are highly fluorescent and regarded as possible candidates for emitting material in organic electronic devices. Although several applications are based on the optical properties of indolizines, only in a few studies have investigated the synthesis and optical properties of indolizine derivatives .…”

Photocatalytic Synthesis of 3‐Sulfanyl‐ and 1,3‐Bis(sulfanyl)indolizines Mediated by Visible Light

“…General Procedure for the Synthesis of 2‐Arylindolizines 1a–d: In a round‐bottomed flask was added the 2‐bromoacetophenone derivative (5.0 mmol), 2‐picoline (0.49 mL, 5.0 mmol) and acetone (20 mL). The resulting mixture was stirred for 4 h under reflux.…”

Funcionalização de compostos N-heterocí­clicos visando a sí­ntese de substâncias bioativas

“…Nesse contexto, dentre os principais grupos dessa classe de reagentes estão os organometálicos de lítio, magnésio e zinco, os quais vêm desempenhando um papel fundamental desde os primórdios da química orgânica sintética (BENISCHKE et al, 2016;MULVEY, 2009;SEYFERTH, 2001 (NISHIMURA et al, 2015;NISHIMURA et al, 2013). Além disso, nosso grupo tem explorado principalmente a metalação de compostos heterocíclicos tais como indolizinas, aril-oxazolinas, tiofenos e quinolinas (Figura 5), visando a obtenção de compostos de interesse, com potencial atividade biológica ou com propriedades fotofísicas, e estudar a influência de grupos dirigentes na regiosseletividade da reação (AMARAL et al, 2014(AMARAL et al, , 2015BATISTA et al, 2015;BOZZINI et al, 2017;DOS SANTOS et al, 2015;MURIE et al, 2018). Nesse contexto, com intuito de prever e racionalizar as reações de metalação, os cálculos computacionais baseados na teoria do funcional de densidade (DFT, do inglês Density Functional Theory) têm desempenhado um importante papel, uma vez que estes possibilitam o cálculo do pKa de hidrogênios presentes nos substratos (BISBALLE et al, 2018;KADIYALA et al, 2013;SNÉGAROFF et al, 2011).…”