1987
DOI: 10.1002/med.2610070202
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Synthesis of vitamin D3and related compounds

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Cited by 75 publications
(31 citation statements)
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“…Stigmasterol is used as a precursor in the manufacture of semisynthetic progesterone, a valuable human hormone that plays an important physiological role in the regulatory and tissue rebuilding mechanisms related to estrogen effects, as well as acting as an intermediate in the biosynthesis of androgens, estrogens, and corticoids. It is also used as the precursor of vitamin D 3 [19,20]. β-sitosterol limits the amount of cholesterol absorption in the intestines, therefore decreasing the levels of cholesterol in the body.…”
Section: Discussionmentioning
confidence: 99%
“…Stigmasterol is used as a precursor in the manufacture of semisynthetic progesterone, a valuable human hormone that plays an important physiological role in the regulatory and tissue rebuilding mechanisms related to estrogen effects, as well as acting as an intermediate in the biosynthesis of androgens, estrogens, and corticoids. It is also used as the precursor of vitamin D 3 [19,20]. β-sitosterol limits the amount of cholesterol absorption in the intestines, therefore decreasing the levels of cholesterol in the body.…”
Section: Discussionmentioning
confidence: 99%
“…15 Stigmasterol, a precursor in manufacturing of semisynthetic progesterone and vitamin D 3 , also an intermediate in biosynthesis of androgens, estrogens and corticoids. 16,17 β-Sitosterol, a potential dietary phytosterol for prevention and therapy for human cancer.…”
Section: Resultsmentioning
confidence: 99%
“…Stigmasterol an unsaturated phytosterol is a precursor of progesterone, which is helpful in tissue rebuilding mechanisms related to estrogen effects, and also acts as an precursor of Vitamin D3 and intermediate in the biosynthesis of androgens, estrogens, and corticoids. [34] Plant also has anti-inflammatory compounds such as 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl (5.46%), and 2-methoxy-4-vinylphenol (0.88%) and few antitumor agents such as delta (2)-angelica lactone (0.42%), tetradecanoic acid and ethyl ester (1.29%), octadecenoic acid and ethyl (Contd...) ester (1.00%), and Vitamin E (0.56%). Some antifungal, antibacterial, and antiviral compounds have also been found, namely 2,4-Dihydroxy-2,5-dimethyl-3(2H)-furan-3-one (0.48%), 2-Hydroxy-1-(1'-pyrrolidiyl)-1-buten-3-one (1.71%), trioxolane (2.78%), pentadecafluorooctanoic acid, and dodecyl ester (1.72%).…”
Section: Discussionmentioning
confidence: 99%