Synthesis of various substituted benzimidazole derivatives using various solvents used for reaction

Abstract

Benzimidazole is the heterocyclic compound formed from benzene and imidazole ring containing nitrogen, oxygen sulphur and its derivatives are of wide interest because of their diverse biological activity. A new method for synthesis of 2-(substituted phenyl)-1Hbenzo[d]imidazole (3a-k) are developed by using simple method, green approach in good yields. We have synthesized 33 molecules in gram scale. This method is extremely useful for the synthesis of benzimidazole derivatives in excellent yields.