Synthesis of some novel 1,2,3-triazole derivatives containing kojic acid moiety and evaluation for their antioxidant activity

Cu-Kojic Acid Complex Anchored to Functionalized Silica-MCM-41: A Promising Regioselective and Reusable Nanocatalyst for Click Reaction

“…The prepared derivatives were indicated their antioxidant activity. 36 This process suffers from one or some disadvantages such as tedious workup, harsh reaction conditions, and longer reaction times. Thus, we became concerned in the development of a clean, efficient, simple, excellent yielding, and eco-friendly method utilizing a novel catalyst for the synthesis of triazoles.…”

Fe3O4@silica‐MCM‐41@DABCO: A novel magnetically reusable nanostructured catalyst for clean in situ synthesis of substituted 2‐aminodihydropyrano[3,2‐b]pyran‐3‐cyano

“…These reactions have many advantages such as the assembly of a product containing considerable elements of all the precursors, simple procedures that make them significant topics in pharmaceutical chemistry and their green chemistry nature . Kojic acid (KA) from the pyrans family, an important heterocyclic compound because of its accessibility, high reactivity and potential biological activity, is used in the medicinal industry and in one‐pot syntheses . In addition, polysubstituted 2‐aminodihydropyrano[3,2‐ b ]pyran‐3‐cyano derivatives are very important heterocyclic compounds, which often exhibit various pharmacological activities .…”

Synthesis and optical properties of novel 1,2,3-triazole derivatives possessing highly substituted imidazoles

“…22,23 1,2,4,5-Tetraarylimidazole derivatives, which can be prepared by four-component condensation of aromatic aldehydes, benzil, primary amines and ammonium acetate, 24,25 have been recently reported by our group 26,27 to act as light-emitting backbones. According to our interest in the synthesis of new heterocyclic and polyaromatic systems containing a 1,2,3-triazole ring, 28 herein we report Cu(I)-catalyzed cycloadditions between azidomethyl derivatives of 1,2,4,5-tetraarylimidazoles and terminal alkynes to afford new 1,2,3-triazole structures possessing polyaryl imidazole scaffolds. In addition, catalytic cyclizations of propargyloxy derivatives of the prepared tetraarylimidazoles with benzyl azide to diversify the products are also reported.…”