Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties

Chiguvare, Herbert; Oyedeji, Opeoluwa O.; Matewu, Reuben; Aremu, Olukayode; Oyemitan, Idris Ajayi; Oyedeji, Adebola O.; Nkeh-Chungag, Benedicta N.; Songca, Sandile P.; Mohan, Sneha; Oluwafemi, Oluwatobi S.

doi:10.3390/molecules21060774

Cited by 30 publications

(16 citation statements)

References 10 publications

(11 reference statements)

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“…Figure 11 shows the peaks near 3000 cm − 1 assigned to O-H stretching and aldehydic C-H stretching. The absorption peaks between 1500 to 2000 cm − 1 can be attributed to the presence of C-O stretching in carboxyl coupled to the amide linkage in amide I which is characteristic of the presence of protein and enzymes in the supernatant and con rms the extracellular formation of AgNPs [34,[63][64][65][66][67]. Consequently, the occurrence of these peaks in the FTIR spectrum evidently indicates the dual role of the M. o cinalis extract, both as a green reducing and stabilizing agents.…”

Section: X-ray Diffraction Analysismentioning

confidence: 91%

Phyto-mediated silver nanoparticles via Mellisa officinalis aqueous and methanolic extracts: synthesis, characterization and biological properties

Nayeri

Mafakheri

Mirhosseini

2020

Preprint

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The aim of the study was to examine the influence of extraction method on the size, shape and morphology of synthesized silver nanoparticles (AgNPs). Silver nanoparticles were prepared by the aqueous and methanolic extracts of lemon balm. The properties of obtained nanoparticles were characterized by UV-Vis, SEM, XRD and FTIR techniques. The UV-Vis spectroscopy confirmed the formation of AgNPs by observing a distinct surface Plasmon resonance band around 450 nm. SEM images showed different shape, size and morphology of AgNPs using two different extracts types. AgNPs derived from the aqueous extract were rod-shaped with a diameter of 19 to 40 nm whereas spherical particles were synthesized by the methanolic extract found smaller with size distribution ranging from 13 to 35 nm. The XRD pattern indicated that AgNPs formed by the reduction of Ag + ions using methanolic extract of M. officinalis were crystal-like in nature. The functional groups of M. officinalis methanolic extract involved in synthesis and stabilization of AgNPs were investigated by FTIR. In addition, AgNPs-containing methanolic extract showed higher antioxidant activity. These particles exhibited remarkable antimicrobial activity against gram positive and negative bacteria and a fungus. The nanoparticles produced by the methanolic extract of the lemon balm showed antioxidant and antimicrobial activity. The production of silver nanoparticles using plant extract is rapid, low cost and eco-friendly. Therefore, green chemistry is a good alternative to industrial production of nanoparticles. Silver nanoparticles can be used as an antiseptic to sterilize the surrounding area and the hospital wastes.

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Section: X-ray Diffraction Analysismentioning

confidence: 91%

Phyto-mediated silver nanoparticles via Mellisa officinalis aqueous and methanolic extracts: synthesis, characterization and biological properties

Nayeri

Mafakheri

Mirhosseini

2020

Preprint

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“…[13], neem leaves [12], aloe vera [14], Parkia speciosa Hassk pods [11]. These plant extracts were used as reducing and stabilizing agents and show antibacterial potency [58][59][60][61][62][63][64][65][66][67][68][69].…”

Section: Silver Nanoparticlesmentioning

confidence: 99%

Inorganic Nanoparticles: An Alternative Therapy to Combat Drug Resistant Infections

Gupta

2021

Int J Pharm Pharm Sci

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One of the most urgent challenges that medical sciences face today is overcoming the problem of drug resistance. This review paper encompasses research studies that provide a solution towards this major concern. It aims to highlight the therapeutic effects of various metal-based nanoparticles over conventional antibiotics. Severe infections caused by bacteria, viruses, fungi and parasites are transmitted easily and spread across millions of people round the globe. Resistance developed by these organisms and their various strains against regular antibiotics has posed great threat to save the lives of humans. Nanoparticles are tiny in nature and thus capable of generating Reactive Oxygen Species (ROS). These ROS bursts to create severe oxidative stresses causing damage to DNA, lipids peroxidation and protein changes resulting in cell death. This mechanism is quite different from traditional antibiotics and hence gives better results towards microbial resistance. The study demonstrates the use of metal nanoparticles such as silver, zinc oxide, aluminium oxide, gold, copper oxide, titanium dioxide, magnesium oxide, iron oxide in combination with various antibiotics to efficiently kill infectious microbes.

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“…Plant extracts contain reducing agents such as the flavonoids, carbohydrates, steroid, sapogenins, and polyphenols which are responsible for the formation of stable silver nanoparticles. Some of the plant extracts used include: Parkia speciosa Hassk pods [ 56 ], neem leaves [ 57 , 58 , 59 ], Catharanthus roseus ( C. roseus ) (L.) G. Don , [ 60 ], aloe vera [ 61 ], apple extract [ 62 ], phlomis [ 63 ], Lycopersicon esculentum [ 64 ], buchu [ 65 ], Ocimum sanctum [ 66 ] etc. These nanoparticles were reported to exhibit antibacterial activity.…”

Section: Bacterial Infectionsmentioning

confidence: 99%

Metal-Based Nanoparticles for the Treatment of Infectious Diseases

2017

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Infectious diseases can be transmitted and they cause a significant burden on public health globally. They are the greatest world killers and it is estimated that they are responsible for the demise of over 17 million people annually. The impact of these diseases is greater in the developing countries. People with compromised immune systems and children are the most affected. Infectious diseases may be caused by bacteria, viruses, and protozoa. The treatment of infectious diseases is hampered by simultaneous resistance to multiple drugs, indicating that there is a serious and pressing need to develop new therapeutics that can overcome drug resistance. This review will focus on the recent reports of metal-based nanoparticles that are potential therapeutics for the treatment of infectious diseases and their biological efficacy (in vitro and in vivo).

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Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties

Cited by 30 publications

References 10 publications

Phyto-mediated silver nanoparticles via Mellisa officinalis aqueous and methanolic extracts: synthesis, characterization and biological properties

Phyto-mediated silver nanoparticles via Mellisa officinalis aqueous and methanolic extracts: synthesis, characterization and biological properties

Inorganic Nanoparticles: An Alternative Therapy to Combat Drug Resistant Infections

Metal-Based Nanoparticles for the Treatment of Infectious Diseases

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