Synthesis of rhodamine based organic nanorods for efficient chemosensor probe for Al (III) ions and its biological applications

Application of a Novel “Turn-on” Fluorescent Material to the Detection of Aluminum Ion in Blood Serum

“…The structure of PPPH and PPPNa was confirmed by 1 H NMR (Figure S1). PPPNa exhibits very good solubility in both water and PBS buffer because of its five carboxylate groups. ,, Adding nonsolvent THF to the PPPNa solution in water results in a photoluminescence (PL) emission enhancement, and the fluorescence intensity increases with the increase of THF fraction [Figure (black square line) and Figure S2]. Compared with that in pure H 2 O, the PL intensity of PPPNa is enhanced ∼28-fold at the THF fraction of 90%.…”

“…It is well known that Al 3+ can act as a “hard” acid to bind “hard” donor sites (N and O atoms) in its coordination sphere. , The deprotonation of carboxylic acid produces −COO – with a high affinity to Al 3+ . ,, It can be conjectured that Al 3+ can bind PPPNa in solution to form PPPNa–Al 3+ complex, and then, the increased aggregation degree can enhance the fluorescent emission of PPPNa because of its AEE property. , Therefore, fluorescence titration was conducted.…”

“…We found in the previous work that 1,2,5-triphenylpyrrole (TPP) derivatives could exhibit aggregation-enhanced emission (AEE) behaviors. The carboxylate-containing TPP derivatives have been successfully used in the detection of Al 3+ in H 2 O/tetrahydrofuran (THF) mixtures based on the “turn-on” AIE mechanism and exhibited high selectivity and sensitivity. ,− However, TPP derivatives are unsuitable for the detection of specific components in pure water and serum. In the present work, we successfully designed and synthesized a water-soluble fluorescent probe, 1,2,3,4,5-penta­(4-carboxyphenyl)­pyrrole sodium salt (PPPNa), with AEE properties as shown in Scheme , which exhibited high selectivity and sensitivity for the detection Al 3+ in both water and phosphate-buffered saline (PBS) buffer.…”

A Bifunctional “Off‐On” Fluorescence Probe Based on Naphthalene for the Detection of Ag+ and Al3+ and Its Application in Practical Water Samples, as a Logic gate and as Test Paper

“…[3][4][5][6][7][8] Besides, excessive exposure to aluminum ions in life has proven harmful to human health, such as senile dementia and cardiovascular and cerebrovascular diseases. [9][10][11][12][13][14] According to the World Health Organization regulations, an adult's daily intake of aluminum can't exceed 10 mg, and the amount of aluminum in the weekly diet is not exceeded 7 mg/ kg. [15][16][17] The enrichment of sliver and aluminum in organisms through the food cycle will cause serious threats to human health and development.…”

A New Red-Emitting Fluorescence Probe for Rapid and Effective Visualization of Bisulfite in Food Samples and Live Animals

“…[19][20][21] Of these methods, fluorescence analysis using responsive fluorescent probe has been recognised as one of the most promising approach for simple, rapid, sensitive and selective detection of target molecules and ions. [22][23][24][25][26][27][28][29] For HSO3detection in food samples and live organisms, a series of fluorescence probes have been developed by using various sensing reaction mechanisms, such as nucleophilic reaction with aldehyde, [30][31][32][33][34] selective deprotection of levulinate, [35][36][37][38] Michael-type additions [39][40][41][42] and coordinative interactions. 43,44 However, there are some unresolved issues for the responsive probes for HSO3detection, such as short-wavelength excitation and emission, unsatisfactory detection limits, long response times (30 min to 10 h) and poor selectivity towards biothiols.…”