Synthesis of polycyclic fused oxazolidin-2-ones by catalytic Boron(III)-Promoted oxo-Michael addition reaction and evaluation on their cytotoxicity

You, Xiao; Hu, Kai-Wen; Zong, Haonan; Wen, Xiaoan; Yuan, Haoliang; Cheng, Keguang; Xu, Qing-Long; Lai, Zengwei

doi:10.1016/j.tet.2023.133714

Tetrahedron

2023

DOI: 10.1016/j.tet.2023.133714

|View full text |Cite

Synthesis of polycyclic fused oxazolidin-2-ones by catalytic Boron(III)-Promoted oxo-Michael addition reaction and evaluation on their cytotoxicity

Xiao You,

Kai-Wen Hu,

Haonan Zong

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Divergent Synthesis of Multisubstituted Hydroindole Derivatives via [3+2] Annulations of p‐Quinamines with Nitroalkenes

Qin,

Liu,

Wan

et al. 2024

Adv Synth Catal

View full text Add to dashboard Cite

The synthesis of two stereoisomers of hydroindole derivatives was achieved through [3 + 2] annulations of p‐quinamines with nitroalkenes. Catalyst‐free or in the presence of DMAP, the annulation reactions were employed to produce the target products containing four contiguous stereogenic centers. This method enables efficient assessment of multisubstituted and functionalized hydroindole derivatives using readily accessible building blocks and reagents. Furthermore, the anti‐inflammatory activity of some resulting hydroindoles was evaluated, with three derivative products showing effective inhibition of NLRP3 inflammasome activation.

show abstract

Divergent Synthesis of Multisubstituted Hydroindole Derivatives via [3+2] Annulations of p‐Quinamines with Nitroalkenes

Qin,

Liu,

Wan

et al. 2024

Adv Synth Catal

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Synthesis of polycyclic fused oxazolidin-2-ones by catalytic Boron(III)-Promoted oxo-Michael addition reaction and evaluation on their cytotoxicity

Cited by 1 publication

References 42 publications

Divergent Synthesis of Multisubstituted Hydroindole Derivatives via [3+2] Annulations of p‐Quinamines with Nitroalkenes

Divergent Synthesis of Multisubstituted Hydroindole Derivatives via [3+2] Annulations of p‐Quinamines with Nitroalkenes

Contact Info

Product

Resources

About