Synthesis of organosilyl compounds-containing 1,2,4,5-tetraaryl imidazoles sonocatalyzed by M/SAPO-34 (M = Fe, Co, Mn, and Cu) nanostructures

Catalytic Synthesis of 1,2,4,5‐Tetrasubstituted 1H‐Imidazole Derivatives: State of the Art

“…[110] In 2015, Safa and coworkers reported that several imidazoles 15 could be prepared in high yields via one-pot cyclo-condensation reactions carried out under ultrasonic irradiation in which Cu(II) nitrate impregnated H-SAPO-34 zeolite was used as catalyst. [111] Karami and coworkers had previously reported that a large variety of tetrasubstituted-1Himidazoles 15 could be obtained in high yields by one-pot four component cyclo-condensation reactions in which, under optimized conditions, 15 mol% Y(NO3)3×6H2O were used as a reusable catalyst. [112] In 2015, sulphated yttria (SO4 2-/Y2O3) was used by Krishnasamy and coworkers as a recyclable catalyst for the synthesis of 1-[2-(2,4,5-triphenyl-1H-imidazol-1-yl)ethyl]piperazine derivatives 40 in 83-93% yield by cyclo-condensation of benzil ( 5), aryl aldehydes 14, 1-N-(2-aminoethyl)piperazine (39) and AcONH4 in EtOH at 80 °C for 10 h (Scheme 29).…”

Synthesis and Applications of 2‐Substituted Imidazole and Its Derivatives: A Review

“…For this reason, recently, many protocols have been developed for the synthesis of imidazole derivatives catalyzed by ionic liquids, using a green catalyst, without the catalyst, reaction under microwave irradiation as well as reaction performed under the solvent‐free condition, which is included in this review. In addition, ultrasound‐promoted synthesis of imidazoles is reported . The present article is intended to briefly review on recent research progress concerning the synthesis of various imidazole derivatives via different methodologies, which mainly includes trisubstituted and tetrasubstituted imidazoles synthesized through different catalysts and conditions.…”

“…Safa and coauthors developed a mild and efficient protocol for the synthesis of 1,2,4,5‐tetraaryl imidazole 18 from the condensation of benzil 14 , aldehyde 15 , amine 16 , and ammonium acetate as an ammonia source using catalyst like Cu/SAPO‐34 in water under ultrasonic irradiation, which afforded high yields of the product (Scheme j) . Here, the authors have studied the optimization using different metals in catalyst M/SAPO‐34 (M: Fe, Co, Mn, and Cu) nanocatalyst, and subsequent silylation reaction (Table ).…”

Piperidinium Hydrogen Sulfate (PHS) as an Efficient Ionic Liquid Catalyst for the Synthesis of Imidazole Derivative under Solvent‐Free Condition

“…This type of reactions has advantages of smooth operation, atom economy, structural diversity, and complexity of the molecules that can be prepared in these reactions. Moreover, multicomponent reactions have a high importance in organic chemistry owing to their various uses in convergent preparation of the organometallic complex molecules from readily and simple available substrates in a single vessel . In this work, we are developing the one‐step construction of an important series of imidazoles compounds by the reaction of benzil with different aldehydes and ammonium acetate using piperidinium hydrogen sulfate (PHS) as an efficient ionic liquid catalyst.…”