Synthesis of Novel Pyrazolylmethylene-Pyrimidine Heterocycles: Potential Synthons for Hybrid Β-Lactams
Abstract:Diversely substituted novel pyrazolylmethylene-pyrimidine heterocycles were synthesized via Knoevenagel condensation between substituted formyl pyrazoles and barbituric acids without any base or solid catalyst. All these thirteen novel heterocycles were characterized by FT-IR, NMR spectroscopy ( 1 H, 13 C), 13 C DEPT-135, 1 H-
13C HSQC, elemental analysis and mass spectrometry (in representative case).
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