Synthesis of novel polyethyleneimine derivatives by stepwise, reversible blocking of primary and secondary amines

Myatt, Elizabeth A.; Scarpa, Ioannis S.

doi:10.1016/0045-2068(90)90024-y

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2023

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Cited by 4 publications

(2 citation statements)

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“…Sample C is acetyl PEI i.e. the water soluble analog of the triflouroacetylcompound used in synthesis (9,10). In sample D, 10% of the total number of amines have been decylated; substitution occurs on the primary (terminal)amines.…”

Section: Peisamplesmentioning

confidence: 99%

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Dynamic light scattering investigations of a new class of polyethyleneimine derivatives

Budzynski¹,

Benight

Myatt

1992

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Section: Peisamplesmentioning

confidence: 99%

“…The extent of each type of modification was determined by C-13 and proton NMR spectra of each polymer (9).…”

Section: Peisamplesmentioning

confidence: 99%

Dynamic light scattering investigations of a new class of polyethyleneimine derivatives

Budzynski¹,

Benight

Myatt

1992

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Liquid nitric oxide donor for adjuvant therapy of acute ischemic stroke via nasal administration

et al. 2023

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Bactericidal Properties of Flat Surfaces and Nanoparticles Derivatized with Alkylated Polyethylenimines

Lin

Qiu

Lewis

et al. 2002

Biotechnology Progress

238

219

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We previously discovered that covalently coating glass and plastic slides with certain long poly(vinyl-N-alkylpyridinium) chains enables the resultant surfaces to kill a variety of airborne and waterborne bacteria on contact. In the present study, these findings have been extended to an unrelated polymer class, polyethylenimines (PEIs). Alkylated PEIs attached to flat macroscopic surfaces and to those of nanoparticles make these materials highly bactericidal toward both Gram-positive and Gram-negative pathogenic bacteria. Systematic chemical modifications of the immobilized PEI conducted herein shed light on the relationship between the structure of the polymer and the antibacterial efficiency of the resultant coating.

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Synthesis of novel polyethyleneimine derivatives by stepwise, reversible blocking of primary and secondary amines

Cited by 4 publications

References 14 publications

Dynamic light scattering investigations of a new class of polyethyleneimine derivatives

Dynamic light scattering investigations of a new class of polyethyleneimine derivatives

Liquid nitric oxide donor for adjuvant therapy of acute ischemic stroke via nasal administration

Bactericidal Properties of Flat Surfaces and Nanoparticles Derivatized with Alkylated Polyethylenimines

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