Liquid nitric oxide donor for adjuvant therapy of acute ischemic stroke via nasal administration

Zhang, Weihang; Chen, Bin; Lin, Run; Dai, Hanren; Zhang, Yan; Qunlong, Mao; Huang, Yonghui

doi:10.1016/j.niox.2023.04.005

Nitric Oxide

2023

DOI: 10.1016/j.niox.2023.04.005

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Liquid nitric oxide donor for adjuvant therapy of acute ischemic stroke via nasal administration

Weihang Zhang

Bin Chen

Run Lin

et al.

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Cited by 2 publications

References 28 publications

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Gas Therapy: Generating, Delivery, and Biomedical Applications

Ghaffari‐Bohlouli,

Jafari,

Okoro

et al. 2024

Small Methods

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Oxygen (O2), nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (H2S), and hydrogen (H2) with direct effects, and carbon dioxide (CO2) with complementary effects on the condition of various diseases are known as therapeutic gases. The targeted delivery and in situ generation of these therapeutic gases with controllable release at the site of disease has attracted attention to avoid the risk of gas poisoning and improve their performance in treating various diseases such as cancer therapy, cardiovascular therapy, bone tissue engineering, and wound healing. Stimuli‐responsive gas‐generating sources and delivery systems based on biomaterials that enable on‐demand and controllable release are promising approaches for precise gas therapy. This work highlights current advances in the design and development of new approaches and systems to generate and deliver therapeutic gases at the site of disease with on‐demand release behavior. The performance of the delivered gases in various biomedical applications is then discussed.

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Gas Therapy: Generating, Delivery, and Biomedical Applications

Ghaffari‐Bohlouli,

Jafari,

Okoro

et al. 2024

Small Methods

View full text Add to dashboard Cite

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Advances in nitric oxide regulators for the treatment of ischemic stroke

Wu,

Jia,

et al. 2023

European Journal of Medicinal Chemistry

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Liquid nitric oxide donor for adjuvant therapy of acute ischemic stroke via nasal administration

Cited by 2 publications

References 28 publications

Gas Therapy: Generating, Delivery, and Biomedical Applications

Gas Therapy: Generating, Delivery, and Biomedical Applications

Advances in nitric oxide regulators for the treatment of ischemic stroke

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