“…In addition, the synthesis of 1,2,4-triazoles has drawn a lot of interest because of the diverse range of pharmacological applications, such as antibacterial, antimycobacterial, antifungal, anti-inflammatory, anticancer, antidiabetic, anti-tubercular, anxiolytics, and anticonvulsants [37][38][39][40]. According to a recent literature review, 1,2,4-triazolo [3,4-b][1,3,4]thiadiazine derivatives have promising biological activities including antibacterial, antifungal, anticancer, anti-HIV, antitubercular, CNS stimulant, antioxidant, anti-inflammatory hypoglycemic, diuretic, and anti-candidal activity [35,[41][42][43][44][45][46]. The above-mentioned observations prompted us to design, synthesis, and test the antibacterial and antifungal activity properties of a series 1,2,3-triazole containing 1,3,4-oxadiazoles with general formula 5 and 1,2,4triazole containing 1,3,4-thiadiazines with general formula 3.…”