2017
DOI: 10.1016/j.jfluchem.2016.12.004
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Synthesis of new (trifluoromethyl)-1H-benzo[e][1,2,4]triazolo[1,2-a][1,2,4]triazine-1,3(2H)-diones and (trifluoromethyl)benzo[5,6][1,2,4]triazino [1,2-b]phthalazine-8,13-diones

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Cited by 7 publications
(1 citation statement)
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“…In the most important drugs which are commercially available, for example antidepressant fluoxetine (Prozac) [25], cholesterol-lowering drug atorvastatin (Lipitor) [26], and the antibacterial ciprofloxacin (Ciprobay), at least one fluorine atom is present [27]. The trifluoromethyl group is becoming more and more important in both of agrochemical and pharmaceutical applications because of the influence of fluorine atom on physical, chemical, and physiological properties, stability, and lipophilicity of the molecule [28][29][30][31]. In recent years, reactions of trifluoromethylation have been extensively investigated, in order to synthesis new organofluorine compounds [32][33][34].…”
Section: Introductionmentioning
confidence: 99%
“…In the most important drugs which are commercially available, for example antidepressant fluoxetine (Prozac) [25], cholesterol-lowering drug atorvastatin (Lipitor) [26], and the antibacterial ciprofloxacin (Ciprobay), at least one fluorine atom is present [27]. The trifluoromethyl group is becoming more and more important in both of agrochemical and pharmaceutical applications because of the influence of fluorine atom on physical, chemical, and physiological properties, stability, and lipophilicity of the molecule [28][29][30][31]. In recent years, reactions of trifluoromethylation have been extensively investigated, in order to synthesis new organofluorine compounds [32][33][34].…”
Section: Introductionmentioning
confidence: 99%