Synthesis of new 1-substituted 4-perfluoroalkyl tetrazol-5-ones

Mekni, Nejib Hussein; Baklouti, A.

doi:10.1016/j.jfluchem.2008.06.019

Cited by 23 publications

(11 citation statements)

References 35 publications

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“…9,10 Tetrazole derivatives have a special structure and can display anti-bacterial properties, such as antiviral and anti-allergic. [11][12][13] There are several methods to prepare tetrazole derivatives, and each method depends on the constituents of the reaction. 14 Recently, there were many various types of compounds (including such containing a metal centre coordinated with suitable ligands) tested against Candida albicans, with a varying degree of success.…”

Section: (Scheme 2)mentioning

confidence: 99%

Synthesis and Characterization of Novel Five-Membered Heterocycles and Their Activity against Candida Yeasts

Tawfeeq

Muslim

Abid

et al. 2019

ACSi

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Some new tetrazole derivatives were prepared by the reaction between the prepared azomethine compounds I 6-I 10 with sodium azide in anhydrous tetrahydrofuran (THF) with a few drops of distilled water and under reflux conditions. Azomethine compounds were prepared by thermal condensation reactions of aromatic aldehydes with primary aromatic amines. The prepared compounds (tetrazole derivatives) were screened for their antibacterial activity (by disc diffusion method). Compound I 6 is the most active derivative that has recorded a significantly (p<0.01) stronger influence to inhibit the growth of Candida zeylanoides with an average zone of inhibition of 26.0 mm. Derivatives I 7 and I 9 showed the lowest zone of inhibition of 8.0 mm against Candida zeylanoides. This study may be helpful in designing more potential anticandidal agents for therapeutic use in the future.

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Section: (Scheme 2)mentioning

confidence: 99%

Synthesis and Characterization of Novel Five-Membered Heterocycles and Their Activity against Candida Yeasts

Tawfeeq

Muslim

Abid

et al. 2019

ACSi

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“…The yield of purifi ed product 100 is unknown [ 39 ]. 1,3-Dipolar cycloaddition of perfl uoroalkylethyl azides to isocyanates afforded 1-perfl uoroalkyl-4-( n -Bu, phenyl or mesitylsulfonyl) tetrazol-5-ones 101 in good yields [ 96 ]. The synthesis of surfactants in the series of fl uoroalkyltetrazoles 102 , 103 and the study of their effect on the surface tension of m -xylene was described by Read et al [ 50 , 97 ].…”

Section: Tetrazolesmentioning

confidence: 99%

Fluorinated Triazoles and Tetrazoles

Островский

Trifonov

2014

Fluorine in Heterocyclic Chemistry Volume 1

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“…However, their chemical reactivity is relatively complex [47]. Many studies describe different positive [48,49] and negative [50] results on their reactivity, adopting different reaction conditions [48][49][50].…”

Section: Introductionmentioning

confidence: 99%

Study of the zinc action on the 2-chloroethyl 2-bromo-2-perfluoroalkylethanoates

Yaich

Amanatoullah

Mekni

2018

Journal of Taibah University for Science

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2-Bromo-2-perfluoroalkyl acids are converted into the corresponding esters by a reaction of alcoholysis in the 2-chloroethanol. The action of zinc on perfluoroalkylated bromo-esters resulted in the bromine reduction products formation via zinc organic intermediates. When heated at 100°C, for 48 h, in the presence of an excess of zinc, the bromo-esters produce the symmetrical bis(vinyl perfluoroalkyl ester) ethoxide compounds, resulting from the BrZnF elimination reaction, followed by a dimerization reaction. ARTICLE HISTORY

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Synthesis of new 1-substituted 4-perfluoroalkyl tetrazol-5-ones

Cited by 23 publications

References 35 publications

Synthesis and Characterization of Novel Five-Membered Heterocycles and Their Activity against Candida Yeasts

Synthesis and Characterization of Novel Five-Membered Heterocycles and Their Activity against Candida Yeasts

Fluorinated Triazoles and Tetrazoles

Study of the zinc action on the 2-chloroethyl 2-bromo-2-perfluoroalkylethanoates

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