Synthesis of Nanoparticles

Kuş, Mahmut; Kırbıyık, Çisem; Baslak, Canan; Kara, Koray; Kara, Duygu Akin

doi:10.1016/b978-0-12-813351-4.00025-0

Cited by 19 publications

(16 citation statements)

References 347 publications

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“…Organic semiconductors seem to be different from the inorganic semiconductors because organic molecules produce solid that resulted from Van-der Waals interactions, whereas inorganic solids created by covalent bonded molecules. That results a weaker intermolecular bonding [19]. However organic semiconductors have lower mobility compared to inorganic materials, where mobility of organic materials can reach 15 cm 2 /V.s [20].…”

Section: Introductionmentioning

confidence: 99%

Numerical Modelling of Carrier Transport in Organic Field Effect Transistors

Hussien

Abdellatif

2022

Preprint

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Organic field effect transistors (OFETs), used in the fabrication of nano-sensors, are one of the most promising devices in the field of organic electronics, because of their light weight, flexible and low fabrication cost. However, the optimization of such OFETs is still in an early stage due to the very limited analytical as well as numerical models presented in the literature. This research presses to demonstrate a numerical carrier transport model based on finite element method (FEM), to investigate the I-V characteristic of OFETs. Two various organic semiconductor materials have been included in the study, polyaniline and pentacene, where a micro-scale as well as a nano-scale models have been presented. OFETs have been studied in terms of channel length, dielectric thickness, and doping level impact. We nominated the threshold voltage, the on/off current ratio, the sub threshold swing, and the field effect mobility’s as the main output evaluating parameters. The numerical model has shown the criticality of the doping effect on tuning the device flowing drain current, to exceed 300 μA saturation current, along with threshold voltage of -0.1 V under a channel length of 30 nm. Additionally, the study highlights the effectiveness of the polyaniline over pentacene as nano-channel length OFET, due to the boosted conductivity of polyaniline with respect to pentacene.

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Section: Introductionmentioning

confidence: 99%

Numerical Modelling of Carrier Transport in Organic Field Effect Transistors

Hussien

Abdellatif

2022

Preprint

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“… 15 − 18 Moreover, toxic reducing agents used in the traditional physicochemical methods for the synthesis of tellurium NPs (TeNPs) are cytotoxic to human cells and environmentally harmful. 19 , 20 To overcome the main limitations of traditional synthesis, efforts have been made to develop nanobiotechnological approaches for the synthesis of TeNPs including tellurite-reducing microorganisms 21 − 23 and plant-derived reducing agents. 15 , 16 , 24 In these cases, the biomolecules involved in tellurium reduction can act as capping agents, providing enhanced stability of the synthesized TeNPs and increased biocompatibility, thus overcoming the major drawbacks of traditional synthesis methods.…”

Section: Introductionmentioning

confidence: 99%

Hybrid Tellurium–Lignin Nanoparticles with Enhanced Antibacterial Properties

Morena

Bassegoda

Hoyo

et al. 2021

ACS Appl. Mater. Interfaces

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The surge of antibiotic-resistant bacteria is leading to the loss of effectiveness of antibiotic treatment, resulting in prolonged infections and even death. Against this healthcare threat, antimicrobial nanoparticles that hamper the evolution of resistance mechanisms are promising alternatives to antibiotics. Herein, we used Kraft lignin, a poorly valorized polymer derived from plant biomass, to develop novel hybrid tellurium–lignin nanoparticles (TeLigNPs) as alternative antimicrobial agents. The sonochemically synthesized TeLigNPs are comprised of a lignin matrix with embedded Te clusters, revealing the role of lignin as both a reducing agent and a structural component. The hybrid NPs showed strong bactericidal effects against the Gram-negative Escherichia coli and Pseudomonas aeruginosa , achieving more than 5 log bacteria reduction, while they only slightly inhibited the growth of the Gram-positive Staphylococcus aureus . Exposure of TeLigNPs to human cells did not cause morphological changes or reduction in cell viability. Studies on the antimicrobial mechanism of action demonstrated that the novel TeLigNPs were able to disturb bacterial model membranes and generate reactive oxygen species (ROS) in Gram-negative bacteria.

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“…Nanoparticles can naturally occur in the environment mediated by biological or geological processes ( Sharma et al, 2015 ), or as incidental by-product of human activities such as smelting or other processes involving the generation of metal fumes ( Gonzalez-Pech et al, 2019 ). In addition, nanoparticles can be artificially synthetized and engineered ( Kus et al, 2018 ). Given the wide variety of existing NPs, classification criteria are also abundant.…”

Section: Nanoparticles As Elements Of Therapy For Malignant Gliomamentioning

confidence: 99%

“…Organic nanoparticles are based on natural compounds such as lipids, glycosides, peptides and others, as well as synthetic organic molecules ( Romero and Moya, 2012 ; Tzeng et al, 2016 ; Kus et al, 2018 ; Karlsson et al, 2019 ; Kozielski et al, 2019 ; Tian et al, 2020 ). These organic elements can arrange themselves in three-dimensional (3D) structures ( Euliss et al, 2006 ), which is one of the main characteristics that differentiate organic from inorganic nanoparticles, as inorganic NPs do not form these 3D structures in any case ( Romero and Moya, 2012 ).…”

Section: Nanoparticles As Elements Of Therapy For Malignant Gliomamentioning

confidence: 99%

Nanoparticles for Stem Cell Therapy Bioengineering in Glioma

Ruiz‐Garcia

Alvarado-Estrada

Krishnan

et al. 2020

Front. Bioeng. Biotechnol.

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Gliomas are a dismal disease associated with poor survival and high morbidity. Current standard treatments have reached a therapeutic plateau even after combining maximal safe resection, radiation, and chemotherapy. In this setting, stem cells (SCs) have risen as a promising therapeutic armamentarium, given their intrinsic tumor homing as well as their natural or bioengineered antitumor properties. The interplay between stem cells and other therapeutic approaches such as nanoparticles holds the potential to synergize the advantages from the combined therapeutic strategies. Nanoparticles represent a broad spectrum of synthetic and natural biomaterials that have been proven effective in expanding diagnostic and therapeutic efforts, either used alone or in combination with immune, genetic, or cellular therapies. Stem cells have been bioengineered using these biomaterials to enhance their natural properties as well as to act as their vehicle when anticancer nanoparticles need to be delivered into the tumor microenvironment in a very precise manner. Here, we describe the recent developments of this new paradigm in the treatment of malignant gliomas.

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Synthesis of Nanoparticles

Cited by 19 publications

References 347 publications

Numerical Modelling of Carrier Transport in Organic Field Effect Transistors

Numerical Modelling of Carrier Transport in Organic Field Effect Transistors

Hybrid Tellurium–Lignin Nanoparticles with Enhanced Antibacterial Properties

Nanoparticles for Stem Cell Therapy Bioengineering in Glioma

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