Synthesis of magnetic core–shell Fe₃O₄@PDA@Cu-MOFs composites for enrichment of microcystin-LR by MALDI-TOF MS analysis

Abstract

The synthetic route of the Fe3O4@PDA@Cu-MOFs microspheres and enrichment process of MC-LR.

Application of aptamer‐conjugated graphene oxide for specific enrichment of microcystin‐LR in Achatina fulica prior to matrix‐assisted laser desorption ionization mass spectrometry

“…In particular, MALDI-MS analysis can simultaneously identify toxin congeners without preceding separation, making it a powerful approach for detecting MCs [18,19]. In a previous study, MALDI-MS has been utilized to detect MCs, but LOD was higher than the official regulatory limit (1 µg/L) of MC-LR in drinking water [20]. Thus, the simple and efficient pre-treated procedures for MC-LR enrichment prior to MALDI-MS analysis are still needed when sensitive detection is desired.…”