Synthesis of Juglone (5-Hydroxy-1,4-Naphthoquinone) in a Falling Film Microreactor

Shvydkiv, Oksana; Limburg, Carolin; Nolan, Kieran; Oelgemöller, Michael

doi:10.1556/jfchem.2012.00022

Cited by 43 publications

(27 citation statements)

References 67 publications

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“…The liquid side mass transfer coefficient

k_{L}

depends on the system scale under study. For micro/milli reactors, an order of magnitude of 10 −4 m·s −1 can be reasonably considered . At last, one finds a minimal value of the Hatta number equals to:

{false(H a false)}_{\min} = \frac{\sqrt{{false(k_{2} false)}_{\min} \cdot C_{B b} \cdot D_{O_{2}}}}{k_{L}} = 6.66.

…”

Section: Resultsmentioning

confidence: 99%

“…Due to various advantages (controlled flow structure, high surface‐to‐volume ratio and enhanced heat and mass transfer), microstructured technologies have received more and more attentions as being promising process intensification technologies enabling to carry out chemical reactions under controlled and safe conditions with high yield and selectivity. Gas/liquid reactions play an important role in scientific research and industrial application fields dealing with flow chemistry: for example, one can cite oxidation, catalytic hydrogenation, and photocatalytic oxidation . When implementing such reactions, it is essential to perfectly characterize and control the mass transfer between both phases insofar as, depending on the chemical kinetics, it can become the limiting step and thus induce a decrease of the reaction performances.…”

Section: Introductionmentioning

confidence: 99%

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Optical methods to investigate the enhancement factor of an oxygen‐sensitive colorimetric reaction using microreactors

et al. 2016

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OATAO is an open access repository that collects the work of Toulouse researchers and makes it freely available over the web where possible. This is an author-deposited version published in : http://oatao. Abstract: Visualization of mass transfer is a powerful tool to improve understanding of local phenomenon. The use of an oxygen-sensitive dye (colorimetric technique 1 ) has showed its relevancy for locally visualizing and characterizing gas-liquid mass transfer at different scales 2,3 . At present, the occurrence of a possible enhancement of the gas-liquid mass transfer by this reaction has not been yet demonstrated. This paper aims at filling this gap by evaluating the Hatta number Ha and the enhancement factor E associated with the oxygen colorimetric reaction when implementing in milli/micro channels. For that, as data on the kinetic of the colorimetric reaction are seldom in the literature, the reaction characteristic time was firstly estimated by carrying out experiments in a microchannel equipped with a micromixer. The diffusion coefficients of dihydroresorufin and O 2 were then determined by implementing two original optical methods in a specific coflow microchannel device, coupled with theoretical modelling. The knowledge of these parameters enabled at last to demonstrate that no enhancement of the gas-liquid mass transfer by this colorimetric reaction existed.Complementary information about the reliability of the colorimetric technique to characterize the gasliquid mass transfer in milli/micro systems was also given.

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“…The liquid side mass transfer coefficient

k_{L}

{false(H a false)}_{\min} = \frac{\sqrt{{false(k_{2} false)}_{\min} \cdot C_{B b} \cdot D_{O_{2}}}}{k_{L}} = 6.66.

…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optical methods to investigate the enhancement factor of an oxygen‐sensitive colorimetric reaction using microreactors

et al. 2016

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“…37,38) Die Arbeiten mit solchen mikrostrukturierten Photoreaktoren konzentrieren sich gegenwärtig darauf, die prinzipielle Durchführ-barkeit von ausgewählten Reaktionen zu zeigen . [39][40][41] Der Fokus dieser Arbeiten im Rahmen der Mikroreaktionstechnik oder auch der Flow Chemistry liegt auf der Herstellung von biologisch aktiven Substanzen für Pharmazeutika, etwa des Antimalariamittels Artimisinin. 42,43) Schwerpunkt dieser Arbeiten sind Geräte für den Laborgebrauch und damit kleine Maßstäbe (Abbildung 5).…”

Section: Photomikroreaktorenunclassified

Technische Chemie 2012

Güttel¹,

Ziegenbalg²,

Greiner³

2013

Nachr Chem

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“…The FFMR has, however, found several successful applications in the field of fast exothermic gas/liquid reactions. [12][13][14][15][16][17] Generally, for enzyme catalysis in microreactors, several factors, such as the complete solubility of all reaction components and high enzyme activity and stability, must be taken into account. The major challenge is the immobilization of active cells or enzymes in or on microchannels.…”

Section: Introductionmentioning

confidence: 99%