Synthesis of isoquinoline derivatives of quinoxalin-2-one from pyrrolo[2,1-a]isoquinoline-2,3-diones and o-phenylenediamine

Reaction of 2,3-dioxopyrrolo[2,1-a]isoquinolines with naphthalene-2,3-diamine

“…We previously studied reactions of 2,3-dioxopyrrolo [2,1-a]isoquinolines with o-phenylenediamine [1,2]. Reactions of these compounds with bulkier binucleophiles were not reported.…”