Synthesis of heterocycles-1. One step synthesis of acetylthiadiazolines

Reactions of hydrazonoyl halides 43 : Synthesis of some new 2,3-dihydro-1,3,4-thiadiazoles, pyrazoles, pyrazolo[3,4-d]-pyridazines, thieno[2,3-b]pyridines, pyrimidino[4′,5′:4,5]thieno[2,3-b]-pyridines and pyrrolo[3,4-d]pyrazoles

“…Elemental analyses were carried out at the Microanalytical Center of the Cairo University. Hydrazonoyl halides were obtained as previously reported [23][24][25][26][27][28][29]. Triethylamine (0.5 g (0.75 mL), 5 mmole) was added dropwise with stirring to a mixture of the appropriate methyl carbodithioate 3, 11a and 11b and the appropriate hydrazonoyl halides 4b-i (5 mmoles) in ethanol (20 ml).…”

2-(4-Naphtho[1,2-d]furan-2-yl-1,3-thiazol-2-yl)-ethanenitrile in Heterocyclic Synthesis

“…Its IR revealed bands at 3349 (NH) and 2221 (CN). Its 13 Compound 2 reacted with phenyl isothiocyanate in N,Ndimethylformamide containing potassium hydroxide to give nonisolable product which converted to a product by hydrochloric acid. The resulting product seems to be one of the four isomers 9a-d (cf.…”

“…Its 1 H NMR showed signals at δ = 2.27 (s, 3H), 7.31-8.10 (m, 13H), and 12,53 (s, br., 1H). 13 (11). Structure 11 was elucidated by elemental analysis and spectral data (cf.…”

Synthesis of 2,3‐dihydro‐1,3,4‐thiadiazole, thiazole, and triazolo[4,3‐a]pyrimidine derivatives from ethyl benzoylacetate

“…Elemental analyses were carried out at the Microanalytical Center of the Cairo University. Hydrazonoyl halides 7a-d were prepared as previously reported [15][16][17][18][19].…”