Synthesis of 2,3‐dihydro‐1,3,4‐thiadiazole, thiazole, and triazolo[4,3‐<i>a</i>]pyrimidine derivatives from ethyl benzoylacetate

Rateb, Nora M.; Abdelhamid, Abdou O.

doi:10.1002/hc.10222

Cited by 13 publications

(5 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The formation of 1,3,4thiadiazole derivatives 5 from the reaction of 1 with 3 seems to follow the sequence outlined in Scheme 1. It is suggested that the reaction starts with nucleophilic substitution of the bromine atom in 3 by the thiolate group of 1 to give the nonisolable intermediate 4 which cyclizes via elimination of aniline [23] to give 5 as end product. The IR spectrum of 5a revealed two carbonyl absorption bands at 1667 (CO ester) and 1628 cm −1 (conjugated CO).…”

Section: Methodsmentioning

confidence: 99%

Utilization of α‐halocarbonyl compounds in the synthesis of thiazole, thiadiazole, and thiophene derivatives

Abdel‐Latif

Bondock

2006

Heteroatom Chemistry

View full text Add to dashboard Cite

The behavior of ethyl 2-phenylthiocarbamoyl acetate 1 toward a variety of several ␣-halocarbonyl compounds was investigated. Thus, reaction of 1 with ␣-bromoketones, hydrazonoyl bromides, and 2-chloro-N-arylacetamides afforded the corresponding dihydrothiazole, 1,3,4-thiadiazole, and thiophene derivatives, respectively. The synthesis of thiazolidin-4one 11, thiazolidin-5-one 12, and some azo derivatives of thiazolidin-5-one were described. 5-Arylazothiazoles 17 and 19 were synthesized by condensation of hydrazonoyl bromides 3 with different thiourea derivatives.

show abstract

Section: Methodsmentioning

confidence: 99%

Utilization of α‐halocarbonyl compounds in the synthesis of thiazole, thiadiazole, and thiophene derivatives

Abdel‐Latif

Bondock

2006

Heteroatom Chemistry

View full text Add to dashboard Cite

show abstract

“…Also, the active methylene group of the thiazolidinone 103 was coupled with different diazonium salts to give the corresponding arylazo derivatives 104 [105]. …”

Section: Electrophilic Coupling Reactionmentioning

confidence: 99%

“…Also, methyl carbodithioate 119 was prepared via reaction of 103 with carbon disulfide in dimethyl formamide and potassium hydroxide followed by iodomethane [105]. …”

Section: Reactions With Phenyl Esothiocyanate and Carbon Disulfidementioning

confidence: 99%

Progress in the chemistry of 4‐ thiazolidinones

Hamama

Ismail

Shaaban

et al. 2008

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

show abstract

“…Compounds studied were prepared and purified by standard procedures cited in the literature [20] see Scheme 1.…”

Section: Compoundsmentioning

confidence: 99%

Electronic Absorption Spectra of Some Triazolopyrimidine Derivatives

Moustafa

Shibl

Hilal

et al. 2011

International Journal of Spectroscopy

View full text Add to dashboard Cite

The electronic absorption spectra of triazolo pyrimidine and some of its derivatives were measured in polar as well as nonpolar solvents. Assignment of the observed transitions is facilitated via molecular orbital calculations. Charge density distributions, dipole moments, and the extent of delocalization of the MOS were used to interpret the observed solvent effects. The observed transitions are assigned as charge transfer (CT), localized, and delocalized according to the contribution of the various configurations in the CI-states. The correspondence between the calculated and experimental transition energies is satisfactory.

show abstract

Synthesis of 2,3‐dihydro‐1,3,4‐thiadiazole, thiazole, and triazolo[4,3‐a]pyrimidine derivatives from ethyl benzoylacetate

Cited by 13 publications

References 15 publications

Utilization of α‐halocarbonyl compounds in the synthesis of thiazole, thiadiazole, and thiophene derivatives

Utilization of α‐halocarbonyl compounds in the synthesis of thiazole, thiadiazole, and thiophene derivatives

Progress in the chemistry of 4‐ thiazolidinones

Electronic Absorption Spectra of Some Triazolopyrimidine Derivatives

Contact Info

Product

Resources

About