Synthesis of green carbon dots as bioimaging agent and drug delivery system for enhanced antioxidant and antibacterial efficacy

Tejwan, Neeraj; Kundu, Mousumi; Ghosh, Noyel; Chatterjee, Sharmistha; Sharma, Anirudh; Singh, Th. Abhishek; Das, Joydeep; Sil, Parames C.

doi:10.1016/j.inoche.2022.109317

Cited by 32 publications

(19 citation statements)

References 76 publications

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“…The 13 C-NMR spectra also revealed that as the reaction progresses, the intensity peaks of the carbon in the aromatic region decrease, and new carbon peaks in the aliphatic and carbonyl group regions are formed, which display enhanced intensity. The ndings of the water solubility and luminescence properties were consistent with the results of the 13 C-NMR analysis. The results demonstrate that utilizing both 13 C-NMR and FTIR spectroscopy gives a more in-depth and precise insight into the formation and structure of carbon dots.…”

Section: Ft-ir Characterization Of the Ncdssupporting

confidence: 85%

“…The ndings of the water solubility and luminescence properties were consistent with the results of the 13 C-NMR analysis. The results demonstrate that utilizing both 13 C-NMR and FTIR spectroscopy gives a more in-depth and precise insight into the formation and structure of carbon dots.…”

Section: Ft-ir Characterization Of the Ncdssupporting

confidence: 85%

“…The FT-IR spectra were obtained in KBr pellets (V max in cm −1 ) on a PerkinElmer spectrophotometer (Waltham, Massachusetts, USA). 13 C-NMR and 1 H-NMR spectra were measured in D 2 O on a Bruker DRX-500 MHz (Billerica, Massachusetts, USA). 1 H-NMR chemical shis were measured in parts per million (ppm) with respect to the residual solvent peak (D 2 O: 1 H = 4.79 ppm).…”

Section: Instrumental Analyses and Ncds Characterizationmentioning

confidence: 99%

“…12 Aqueous soluble CDs with good water solubility are widely studied in chemical and biological sensors, pharmaceutical and gene delivery, and bioimaging systems. [13][14][15] CDs have been created using a variety of synthetic approaches from various sources of raw materials. The two primary methods for CD synthesis are top-down and bottom-up.…”

Section: Introductionmentioning

confidence: 99%

“…In this work, based on the hydrolysis of cyclic amides and noncovalent p-p stacking interactions, highly water-soluble blue emission NCDs with high yield (40%) and quantum yield (18%) from 4-aminoantipyrine as a precursor by the hydrothermal method in deionized water at 180 °C with different the reaction times from 3-21 h have been synthesized. The mechanism and structure of NCDs formation have been investigated using spectroscopic techniques such as FT-IR, 13 C-NMR, 1 H-NMR, and UV-visible, which have not been widely utilized for this purpose previously.…”

Section: Introductionmentioning

confidence: 99%

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Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, ¹³C-NMR, ¹H-NMR, and UV-visible spectroscopic approaches

2023

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Section: Ft-ir Characterization Of the Ncdssupporting

confidence: 85%

Section: Ft-ir Characterization Of the Ncdssupporting

confidence: 85%

Section: Instrumental Analyses and Ncds Characterizationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, ¹³C-NMR, ¹H-NMR, and UV-visible spectroscopic approaches

2023

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Antibacterial Carbon Dots: Mechanisms, Design, and Applications

Zhao

Liu

Wang

et al. 2023

Adv Healthcare Materials

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The increase in antibiotic resistance promotes the situation of developing new antibiotics at the forefront, while the development of non‐antibiotic pharmaceuticals is equally significant. In the post‐antibiotic era, nanomaterials with high antibacterial efficiency and no drug resistance make them attractive candidates for antibacterial materials. Carbon dots (CDs), as a kind of carbon‐based zero‐dimensional nanomaterial, are attracting much attention for their multifunctional properties. The abundant surface states, tunable photoexcited states, and excellent photo‐electron transfer properties make sterilization of CDs feasible and are gradually emerging in the antibacterial field. This review provides comprehensive insights into the recent development of CDs in the antibacterial field. The topics include mechanisms, design, and optimization processes, and their potential practical applications are also highlighted, such as treatment of bacterial infections, against bacterial biofilms, antibacterial surfaces, food preservation, and bacteria imaging and detection. Meanwhile, the challenges and outlook of CDs in the antibacterial field are discussed and proposed.

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Pharmacognostic standardization of Rhododendron afghanicum through scanning electron microscopy and analytical techniques

Alam

Ahmad

2022

Microscopy Res & Technique

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The aim of this study was to assess and compare the pharmacognostic and microscopic features of the selected parts of Rhododendron afghanicum Aitch. & Hemsl. It is a perennial and shrub. Anatomy of stem and leaves depicted dicot structure. It will provide knowledge about standardization, authentication, and adulteration with its co‐species. The macroscopic examination reveals that fresh leaves are green, pleasant odor with a bitter taste. The leaf is oblong‐elliptic in shape and sub‐acute at apex; rounded at the base with entire margin. Stem is irregular and the outer surface is light brown, rough with fissures and ridges. Microscopic examination indicated the presence of xylem, phloem, peltate trichome, epidermal cells, collenchymas cells, paracytic stomata, and reticulate vessels. Stem microscopy reveals epidermis, hypodermis, cortex, sclerenchymatous sheath, phloem, xylem, and pith. It will be helpful in identification and quality control. Micro‐morphological features were observed through SEM. EDX spectroscopy were carried out and revealed the presence of calcium, silicon, and potassium. Phytochemical analysis revealed the presence of tannins, saponins, phenols, protein, flavonoids, glycosides, and alkaloids. Ethyl acetate for leaf and stem demonstrate the highest extractive values (18% and 13%), respectively. XRD peaks appeared at 30.21, 28.73, 205.73, 200.73, 380.07, 390.24, 490.11, and 450.33ο. This will be helpful to identify the ownership of herbal drugs by the diffraction peaks through crystal structures and atomic spacing. These parameters are crucial for drug identification, standardization, authentication, and drug designing. These studies also provided knowledge regarding therapeutic and nutraceutical importance of this plant. Research Highlights The current pharmacognostic studies carried out on Rhododendron afghanicum can serve as a basis for compiling keys for finding the taxonomic identification and authentication of the said species by morphological, anatomical, and physicochemical features.

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Synthesis of green carbon dots as bioimaging agent and drug delivery system for enhanced antioxidant and antibacterial efficacy

Cited by 32 publications

References 76 publications

Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, ¹³C-NMR, ¹H-NMR, and UV-visible spectroscopic approaches

Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, ¹³C-NMR, ¹H-NMR, and UV-visible spectroscopic approaches

Antibacterial Carbon Dots: Mechanisms, Design, and Applications

Pharmacognostic standardization of Rhododendron afghanicum through scanning electron microscopy and analytical techniques

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Synthesis of green carbon dots as bioimaging agent and drug delivery system for enhanced antioxidant and antibacterial efficacy

Cited by 32 publications

References 76 publications

Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, 13C-NMR, 1H-NMR, and UV-visible spectroscopic approaches

Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, 13C-NMR, 1H-NMR, and UV-visible spectroscopic approaches

Antibacterial Carbon Dots: Mechanisms, Design, and Applications

Pharmacognostic standardization of Rhododendron afghanicum through scanning electron microscopy and analytical techniques

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Product

Resources

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Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, ¹³C-NMR, ¹H-NMR, and UV-visible spectroscopic approaches

Deep insights to explain the mechanism of carbon dot formation at various reaction times using the hydrothermal technique: FT-IR, ¹³C-NMR, ¹H-NMR, and UV-visible spectroscopic approaches