Synthesis of Crescent Aromatic Oligoamides

Abstract

[structures: see text] This article describes the synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in recent years in our laboratory. The large-scale preparation of a variety of monomers derived from various tetrasubstituted benzenes is presented. Three different strategies for constructing various oligomers consisting of meta- and meta/para-linked benzene residues are discussed. Factors affecting coupling efficiency and yields are analyzed. The developed synthetic methods have provided the basis for the preparation of longer oligomers and for the development of solid-phase synthesis.

Conformational Control in Metallofoldamers: Design, Synthesis and Structural Properties

“…In attempts to control the absolute helicity of the metallofoldamer, a different salophen (oligomeric ligand 6, Figure 5) was designed to stabilize the (M)-helix by a threecenter hydrogen bond [20] while destabilizing the (P)-helix through steric interference of the amide carbonyl, by ad- ditional ester functions. Accordingly, ligand 6 was synthesized and mixed with Ni(OAc) 2 to obtain the corresponding Ni complex (oligomer 5, Figure 5).…”

Shape-persistent macrocycles: efficient extraction towards lanthanide and actinide elements

“…They were dried under vacuum for at least 48 h before use and the concentrations of their stock solutions were standardized by complexometry using xylenol orange as coloured indicators [23,24]. 1,5-Dimethoxy-2,4-diaminobenzene 3 and 2,4-dimethoxy-5-nitroaniline 7 were obtained from reduction of 1,5-dimethoxy-2,4-dinitrobenzene [25]. Diacid chlorides 6 (a, b, c) were prepared from oxalyl chloride and their corresponding diacids, and 4 was synthesized according to similar literature procedures [25].…”

Hydrogen‐Bonded Shape‐Persistent Aryl Hydrazide Polymers: Side‐Chain‐Tuned Formation of Vesicles and Organogels

“…Polymer P4 was prepared from the reaction of 10 and 11 [32] as a white solid according to a procedure similar to that for the preparation of P1.…”