Synthesis of Core−Shell Structured Dual-Mesoporous Silica Spheres with Tunable Pore Size and Controllable Shell Thickness

Abstract

Core-shell structured dual-mesoporous silica spheres (DMSS) that possess smaller pores (2.0 nm) in the shell and larger tunable pores (12.8-18.5 nm) in the core have been successfully synthesized by utilizing an amphiphilic block copolymer (polystyrene-b-poly (acrylic acid), PS-b-PAA) and cetyl trimethyl ammonium bromide (CTAB) as cotemplates. The thickness of the shells and the larger pore size in the core could be easily tuned by changing the amounts of TEOS and the hydrophobic block (PS) length during synthesis, respectively. By encapsulating hydrophobic magnetite nanoparticles into the cores, superparamagnetic dual-mesoporous silica spheres were obtained. Drug storage and release testing results showed that the diffusing rate of the stored drug could be efficiently controlled by changing the shell thickness of DMSS.

Preparation and characteristics of Fe3O4@YVO4:Eu3+ bifunctional magnetic–luminescent nanocomposites

“…Magnetic nanoparticles have been extensively studied in the fields of biomedical applications, including magnetic resonance imaging (MRI), gene/drug delivery, and biosensors, as well as biochemical separation and concentration of trace amount of samples [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Luminescent nanoparticles have attracted great attention in the field of biological labeling [15][16][17][18].…”

Synthesis of Core-shell Structured Porous Materials and Applications as Catalysts and Precursors for Hollow Porous Materials

“…However, only a few studies on the fabrication and their application have been reported 44) 46) . Core-shell structured dual-mesoporous silica spheres with larger mesopores in the core were formed 44) . Preparation of novel mono-dispersed silica spheres with mesopores in the radial orientation was reported 47) , and growth of the spheres could be obtained with mercaptopropyl-modified silica to form a core-shell structure 45) .…”

Preparation of core–shell mesoporous silica nanoparticles with bimodal pore structures by regrowth method

“…synthesized core-shell structured MSNs with large pores in the cores and both large and small pores in the shells using an amphiphilic block copolymer (polystyrene-b-poly(acrylic acid)) and cetyltrimethylammonium bromide (CTAB) [25]. Most recently, Shen et al reported the preparation of dendritic MSNs with radial mesopores, where the pore size of each generation can be adjusted using varied hydrophobic solvents in the oil-water biphasic systems [26].…”