Synthesis of Chitosan Protected Nickel Hexacyanoferrate Modified Titanium Oxide Nanotube and Study its Application on Simultaneous Electrochemical Detection of Paracetamol and Caffeine

Abstract

The nickel hexacyanoferrate decorated titanium oxide nanotube (NiHCF@TNT) was prepared by ion exchange method by mixing of nickel ion modified titanium oxide nanotube with a known amount of potassium ferricyanide under stirring over a period of 5 h. The resulting product was isolated and then characterized with XRD, FT-IR and SEM. The electrochemical behaviour of NiHCF@TNT was investigated by cyclic voltammetry using chitosan as stabilizing agent. The electrocatalytic property of chitosan protected NiHCF@TNT was carried out on electrochemical oxidation of paracetamol and caffeine simultaneously. The proposed method may be applied for the electrochemical detection of paracetamol in drug samples. _______________________________________________________________________________