Synthesis of 2‐substituted‐2,3‐dihydro‐5‐benzoyl‐1 H ‐1,3,2‐benzodiazaphosphole 2‐oxides/sulfides

Krishna

Journal of Chemical Research

et al. 2009

Self Cite

A series of some new class of 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides 4a-j were synthesised by reacting 3,4-diaminobenzophenone (3) with various dichlorophosphinyl carbamates (2) in dry toluene-tetrahydrofuran mixture (1:1) in the presence of triethylamine at 45-50°C. All the title compounds were evaluated for antimicrobial activity to determine their efficacy and were effective in suppressing the growth of bacteria and fungi. The chemical structures of the title products were characterised by IR, 1 H, 13 C and 31 P NMR and mass spectral studies.

Section: Ytterbium (Iii) Triflate Catalysed [3 + 2] Cycloaddition Involving Isothiocyanates and Epichlorohydrinmentioning

confidence: 99%

Synthesis, Characterisation and Antimicrobial Activity of Novel 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides

Krishna

Journal of Chemical Research

et al. 2009

Self Cite

“…Phosphocin/phosphepin and their related derivatives containing this group represent an important class of pesticides, antibiotics, herbicides and antiviral agents (Vasu Goverdhana Reddy et al, 2002). Some of them are well known for their insecticidal activities (Schrader, 1957) and are known to degrade hydrolytically and enzymatically to non-toxic residues.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, spectral, and antimicrobial evaluation of some new 8-membered phosphorus heterocyclic compounds

Sankar

et al. 2010

Med Chem Res

Synthesis of 9-substituted-8, 9 10, 11-tetrahydro-7H-7, 11-diaza-9k 5 -phosphacycloocta [d,e] naphthalene-9-sulfides/selenides (4-13) was accomplished in three steps. 1,8-diamino naphthalene (2) was reacted with tris (bromomethyl) phosphine (1) in the presence of triethylamine in dry tetrahydrofuran (THF) under N 2 atmosphere to form the corresponding intermediate (3). It was converted to the corresponding sulfide (4) and selenide (5) by the reaction with sulfur and selenium, respectively. The intermediates 4 and 5 were reacted with two achiral alcohols and two achiral amines to obtain the title compounds (6-13). The structures of the title compounds were established by elemental analysis and spectral data (IR, 1 H, 13 C, 31 P NMR, and FAB mass). The antimicrobial activity of these compounds was evaluated and they exhibited significant activity.

Phosphorus, Sulfur, and Silicon and the Related Elements

“…These are being used as pesticides, insecticides, fungicides, and bactericides. [1][2][3] Various phosphorylated compounds of benzothiazole and amines are also associated with antifungal activities. [4][5][6] In continuation of our previous work, 7 we report herein the synthesis, characterization, and antifungal activity of some phosphorylated and thiophosphorylated benzothiazole derivatives.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Spectral, and Antifungal Evaluation of Phosphorylated and Thiophosphorylated Benzothiazole Derivatives

Mittal

Samota

Kaur

et al. 2007

The phosphorylated and thiophosphorylated benzothiazole derivatives have been synthesized by the reaction of phosphorus oxychloride/phosphorus thiochloride with 2-(2 -aminophenyl)benzothiazole in 1:1, 2:1, 3:1, and 1:2 molar ratios in presence of triethylamine. Plausible structures have been proposed on the basis of elemental analysis IR, 1 H NMR, 31 P NMR, and mass spectral studies. The fungicidal activity of these derivatives have been evaluated against pathogenic fungi Aspergillus niger and Fusarium oxysporium. The fungicidal data reveals that these compounds are more fungitoxic than the parent 2-(2 -aminophenyl)benzothiazole compound.