“…MCRs allow the creation of several bonds in a single operation and offer remarkable advantages like simple procedure, high bond forming efficiency, time and energy saving, extraction and purification processes, and hence minimize waste generation [6][7][8][9][10]. MCRs are useful for the expedient creation of chemical libraries of drug-like compounds with high levels of molecular complexity and diversity, thereby facilitating identification/optimization in drug discovery programmes [11][12][13][14][15][16]. Therefore, researchers have made great efforts to develop new MCRs with green procedure, especially in the areas of drug discovery, organic synthesis, and material science [17,18].…”