Synthesis, characterization, single crystal X-ray structure determination and packing analysis of thallium(I) anthracene-9-carboxylate, [Tl 4 (H 2 O) 2 (anthracene-9-carboxylate) 4 ]

Kumar, Santosh; Sharma, Raj Pal; Saini, Anju; Venugopalan, Paloth; Starynowicz, Przemysław

doi:10.1016/j.molstruc.2014.09.027

Cited by 5 publications

(4 citation statements)

References 49 publications

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“…3-amino-4-methylfurazan (Pibiri et al, 2018) and 4-amino-1,2,5-oxadiazole-3carboxamide oxime (Zhang & Jian, 2009). Tl I complexes with comparable organic ligands have been reported for thallium (anthranoyl)anthranilate (Wiesbrock & Schmidbaur, 2004), thallium(I) 2-amino-benzoate (Wiesbrock & Schmidbaur, 2003), thallium(I) arylcyanoxime (Robertson et al, 2004) [Tl 4 (H 2 O) 2 (anthracene-9-carboxylate) 4 ] (Kumar et al, 2015) (Britton, 2001) and thallium(I) 4-hydroxybenzylidene-4-aminobenzoate (Akhbari et al, 2009).…”

Section: Database Surveymentioning

confidence: 68%

Crystal structure of poly[(μ₃-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]

et al. 2020

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The title compound represents the thallium(I) salt of a substituted 1,2,5-oxadiazole, [Tl(C3H3N4O3)] n , with amino- and hydroxamate groups in the 4- and 3- positions of the oxadiazole ring, respectively. In the crystal, the deprotonated hydroxamate group represents an intermediate between the keto/enol tautomers and forms a five-membered chelate ring with the thallium(I) cation. The coordination sphere of the cation is augmented to a distorted disphenoid by two monodentately binding O atoms from two adjacent anions, leading to the formation of zigzag chains extending parallel to the b axis. The cohesion within the chains is supported by π–π stacking [centroid–centroid distance = 3.746 (3) Å] and intermolecular N—H...N hydrogen bonds.

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Section: Database Surveymentioning

confidence: 68%

Crystal structure of poly[(μ₃-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]

et al. 2020

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“…The chemical properties of Tl(I) such as the presence of lone electron pair, large size, salts that are often anhydrous, diverse coordination numbers, and geometries have caused that, despite high toxicity, its coordination compounds be especially regarded 8 . The evaluations on the toxicity rate of thallium show that coordinating with some organic molecules has a significant role in the reduction of its toxicity rate 9 .…”

Section: Introductionmentioning

confidence: 99%

“…But besides the role of metal and its oxidation state, the nature of ligand coordination should not be ignored to evaluate the cytotoxicity effects of metallic complexes. It has been proven that versatile anionic ligands including carboxylate groups with diversity in the coordination modes are usually favorable options to design metal complexes and an assay of their medicine activity 8 . In 2005, M. Rafizadeh et al, synthesized the thallium(I) complex containing 2,6-Pyridinedicarboxylic acid (pydcH 2 ) and reported its crystal structure 19 .…”

Section: Introductionmentioning

confidence: 99%

Novel Tl(III) complexes containing pyridine-2,6-dicarboxylate derivatives with selective anticancer activity through inducing mitochondria-mediated apoptosis in A375 cells

Abdolmaleki

Ghadermazi

Aliabadi

2021

Sci Rep

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Three novel Tl(III) complexes (C1), (C2) and (C3) were synthesized using the one-pot reactions of pyridine dicarboxylic acid derivatives, 2-aminobenzimidazole and/or 4-aminopyridine, and also thallium(III) nitrate trihydrate metal salt. The structure of all three complexes was determined by the single-crystal X-ray diffraction. C1 and C2 were realized to be isostructural with disordered square anti-prismatic geometry and for C3 arrangement of the distorted tricapped triangular prism was proposed. Cyclic voltammetry measurements on the complexes exhibited that formal potential values are more positive for C1 (E0ˊ 0.109 V) and C3 (E0ˊ 0.244 V) compared to C2 (E0ˊ –0.051 V), versus Ag/AgCl under argon. Moreover, cytotoxicity of the compounds was evaluated in vitro against two cancer cell lines including a human melanoma (A375), a human colon adenocarcinoma (HT29), and also one normal cell human foreskin fibroblast (HFF). The selective and potent cytotoxicity effect was exhibited by C1 and C3 on cancer cell lines. The apoptosis through a caspase-dependent mitochondrion pathway was confirmed by ROS production, MMP reduction, p53 activation, Bax up-regulation, and Bcl-2 down-regulation, cytochrome c release, procaspase-9, and 3 expression, for A375 cells treated to C1 and C3. According to similar cellular uptake of the complexes in A375 cell line, the generation of ROS was considered as an effective agent to justify the inhibition effect C1 and C3 on mentioned cells. Furthermore, arresting the cell cycle in the G2-M phase and inducing apoptosis were indicated by these two complexes.

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“…Metal complexes of sulpha drugs have been reported with appreciable biological activities [ 23 , 24 , 25 , 26 , 27 , 28 ]. Recently, there have been several reports on neodymium(III) and thallium(III) complexes [ 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 ]. Mimouni et al, 2014 [ 38 ] have synthesized, characterized, and studied the antibacterial, antifungal and antitubercular activities of thallium complexes of monensin and lasalocid.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization and Antibacterial Studies of N-(Benzothiazol-2-yl)-4-chlorobenzenesulphonamide and Its Neodymium(III) and Thallium(III) Complexes

et al. 2017

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N-(Benzothiazol-2-yl)-4-chlorobenzenesulphonamide (NBTCS) was synthesized by condensation reaction of 4-chlorobenzenesulphonyl chloride and 2-aminobenzothiazole in acetone under reflux. Neodymium(III) and thallium(III) complexes of the ligand were also synthesized. Both ligand and metal complexes were characterized using UV-Vis, IR, 1H- and 13C-NMR spectroscopies, elemental analysis and molar conductance measurement. IR studies revealed that the ligand is tridentate and coordinates to the metal ions through nitrogen and oxygen atoms of the sulphonamide group and nitrogen atom attached to benzothiazole ring. The neodymium(III) complex displays a coordination number of eight while thallium(III) complex displays a coordination number of six. The ligand and its complexes were screened in vitro for their antibacterial activities against Escherichia coli strains (E. coli 6 and E. coli 13), Proteus species, Staphylococcus aureus and Pseudomonas aeruginosa using the agar well diffusion technique. The synthesized compounds were found to be more active against the microorganisms screened relative to ciprofloxacin, gentamicin and co-trimoxazole.

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Synthesis, characterization, single crystal X-ray structure determination and packing analysis of thallium(I) anthracene-9-carboxylate, [Tl 4 (H 2 O) 2 (anthracene-9-carboxylate) 4 ]

Cited by 5 publications

References 49 publications

Crystal structure of poly[(μ₃-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]

Crystal structure of poly[(μ₃-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]

Novel Tl(III) complexes containing pyridine-2,6-dicarboxylate derivatives with selective anticancer activity through inducing mitochondria-mediated apoptosis in A375 cells

Synthesis, Characterization and Antibacterial Studies of N-(Benzothiazol-2-yl)-4-chlorobenzenesulphonamide and Its Neodymium(III) and Thallium(III) Complexes

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Synthesis, characterization, single crystal X-ray structure determination and packing analysis of thallium(I) anthracene-9-carboxylate, [Tl 4 (H 2 O) 2 (anthracene-9-carboxylate) 4 ]

Cited by 5 publications

References 49 publications

Crystal structure of poly[(μ3-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]

Crystal structure of poly[(μ3-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]

Novel Tl(III) complexes containing pyridine-2,6-dicarboxylate derivatives with selective anticancer activity through inducing mitochondria-mediated apoptosis in A375 cells

Synthesis, Characterization and Antibacterial Studies of N-(Benzothiazol-2-yl)-4-chlorobenzenesulphonamide and Its Neodymium(III) and Thallium(III) Complexes

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Crystal structure of poly[(μ₃-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]

Crystal structure of poly[(μ₃-4-amino-1,2,5-oxadiazole-3-hydroxamato)thallium(I)]