Synthesis, characterization, and thermodynamics of some new unsymmetrical Schiff bases of salicylaldehyde with 3,4-diaminopyridine and their cobalt(III) complexes

Asadi, Mozaffar; Torabi, Susan; Mohammadi, Khosro

doi:10.1016/j.saa.2013.09.098

Cited by 14 publications

(14 citation statements)

References 25 publications

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“…The amount of residue remaining at the end of the decomposition coincides exactly with that calculated, 12 The first observation of thermogravimetric analysis of the complexes of cadmium(II) with Schiff bases bpbpd and bpepd is that on heating, they are stable up to about 200°C (Figs. 8,9).…”

Section: Thermal Analysis Of [Ni(bpbpd)(h 2 O) 2 ](No 3 )supporting

confidence: 81%

“…Proteins, some vitamins and enzymes contain metal ions in their structure involving macromolecular ligands. The chemistry of metal complexes with multidentate ligands having delocalized p-orbitals, such as Schiff bases or porphyrins, has recently gained more attention because of their use as models in biological systems [10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

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New complexes with 2-pyridyl ketone Schiff bases

Popescu

Rotaru

Bubulica

et al. 2015

J Therm Anal Calorim

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Seven new complexes of 2-pyridyl ketone Schiff bases N,N 0 -bis-(pyridin-2-yl-benziliden)-propan-1,3diamine (bpbpd) and N,N 0 -bis-[1-(pyridin-2-yl)-etiliden]propan-1,3-diamine (bpepd) with Co(II), Ni(II), Zn(II) and Cd(II) nitrates and perchlorates were synthesized and investigated using elemental analysis, spectroscopic techniques (IR and UV-Vis-NIR) as well as magnetic and conductometric measurements. The structure of a cadmium(II) complex was accomplished by single-crystal X-ray diffraction. The Schiff base ligands act as NNNN tetradentate ligands coordinating through pyridine nitrogens and azomethine nitrogens to transition metal ions. The metal ions are six-coordinate for Co(II) and Ni(II), fourcoordinate in the case of Zn(II) and eight-coordinate for Cd(II) ions. The coordination sphere of cobalt and nickel complexes is completed by two water molecules, resulting a distorted octahedron. In the case of zinc(II) complexes has been proposed a distorted tetrahedral geometry. The Cd(II) ions are surrounded by a tetradentate Schiff base ligand and two bidentate nitrate anions, leading to a dodecahedral coordination environment. Thermal decomposition of these compounds is a multistage process. Generally, water elimination occurs in the first step and the decomposition of nitrate groups and organic ligands in the next stages. The last step of decomposition for all complexes is strong exothermic and corresponds to oxidative combustion of the Schiff base ligand.

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Section: Thermal Analysis Of [Ni(bpbpd)(h 2 O) 2 ](No 3 )supporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

New complexes with 2-pyridyl ketone Schiff bases

Popescu

Rotaru

Bubulica

et al. 2015

J Therm Anal Calorim

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“…The spectrum showed multiplet signals at 4.24–4.78 ppm which corresponded to ferrocene group . The methyl protons of ferrocene group were appeared at 1.22 ppm while the methyl protons of alanine were appeared at 2.35 ppm . Also, proton of (CH group) of alanine moiety was appeared as multiplet signals in the range of 6.42–6.44 ppm .…”

Section: Resultsmentioning

confidence: 96%

Transition metal complexes of nano bidentate organometallic Schiff base: Preparation, structure characterization, biological activity, DFT and molecular docking studies

Mahmoud

Deghadi

Desssouky

2018

Applied Organom Chemis

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An organometallic NO-bidentate Schiff base, (2-(1-((1-carboxyethyl)imino) ethyl) cyclopenta-2,4-dien-1-yl)(cyclopenta-2,4-dien-1-yl) iron (HL) was synthesized by condensation of 2-acetylferrocene with amino acid alanine. Then its octahedral Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Cu (II), Zn (II) and Cd (II) complexes were synthesized. All compounds were characterized on the basis of elemental analysis (C, H, N and M), molar conductivity, FT-IR, UV-Vis, 1 H-NMR, SEM, mass analysis and thermal studies. Furthermore, computational studies of HL ligand have been carried out by DFT/B3LYP method. HOMO and LUMO energy values, chemical hardness-softness, electronegativity, electrophilic index and other parameters were calculated. SEM micrographs of HL ligand and its [Cd (HL)(H 2 O) 2 Cl 2 ].2H 2 O complex, showed that they were prepared in nano-structure forms with particle size 54 and 41 nm, respectively. Antifungal and antibacterial activities of HL ligand and its metal complexes have been screened in vitro against different species such as Aspergillus fumigatus, Candida albicans, Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Salmonella typhimurium. The synthesized compounds were evaluated for their anticancer activities against breast cancer cell line (MCF-7) and normal melanocytes cell line . It was found that [Co (HL)(H 2 O) 2 Cl 2 ].3H 2 O complex had the lowest IC 50 value (10.9 μg/ml) and hence was the most active one. Finally, the optimized structures of the Schiff base and its Co (II) complex have been used to accomplish molecular docking studies with receptors of 3HB5, 3MIW, 5IBV and 4WM8 to determine the most preferred mode of interaction.

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“…The elemental analysis and some physical data for the complexes are listed in Table 1. [18,21] (Table 2). …”

Section: Resultsmentioning

confidence: 99%

“…[16] Many experimental and theoretical investigations have been done on cobalt Schiff base complexes because of their interesting drug properties such as antiviral drugs. [17] In continuation of our works on the unsymmetrical Schiff base complexes, [18][19][20][21] we synthesized and characterized some new unsymmetrical cobalt(III) Schiff base complexes. The formation constants and the thermodynamic parameters were determined spectrophotometrically for 1 : 1 adduct formation of the new complexes as acceptor with some aliphatic amines such as benzylamine, n-butylamine, sec-butylamine and tert-butylamine as donors in DMSO solvent with the goal of evaluating the effect of axial ligands and the substituted equatorial Schiff base ligands.…”

Section: Introductionmentioning

confidence: 99%