Synthesis, Characterization and Spectral Studies of Noble Heterobinuclear Complexes of Transition Metal Ions and their Biological Activity

Abstract

Some noble heterobinuclear complexes of transition metal ions with bis(salicylaldehyde)malonyl-dihydrazone in the presence of 5-nitroindazole Cu(II) / Ni(II)- chloride of the type [ML1M‘L2Cl2] or [ML1FeL2Cl2]Cl, where M = Ni(II), Cu(II) and M' = Mn(II), Co(II), have been prepared. All the complexes have been characterized by IR, UV vis and EPR spectroscopy, elemental analysis, magnetic moment and molar conductance measurement. Spectral studies and magnetic moment measurement in DMF suggest the covalent nature of the complexes, except the [ML1FeL2Cl2]Cl complex which is 1:1 electrolyte. An octahedral geometry is proposed for M‘ and square planer for M for the heterobinuclear complexes. The low value of magnetic moment and overlapping EPR signals are due to spin crossover since both of the metals have unpaired electrons with same molecular symmetry. The lowering of the magnetic moment has been discussed. The biological activity (antifungal and antibacterial) of the represented compounds has been studied.

Synthesis, Characterization, and DFT Calculations of a New Sulfamethoxazole Schiff Base and Its Metal Complexes

“…The shift of two sulfonamide vibrations (the symmetric as well as the asymmetric one [ 60 ]) toward a lower shift number in the spectra of the complexes as compared to the spectra of corresponding ligands ( Table 2 ) further supports (M-O) bonding [ 3 ]. The new bands observed at 430–572 cm −1 are tentatively assigned to ν (M-N) and (M-O) (metal–ligand) [ 61 , 62 ]. The metal complexes show a broad band in the region 3467, 3387, and 3397 cm −1 and a new band at 825, 833, and 825 cm −1 that is assigned to the (O-H) stretching vibration and out-of-plane bending of water molecules coordinated to the complexes L 1 , L 2 , and L 3 , respectively [ 63 ].…”

Synthesis, Characterization and Antimicrobial Studies of Novel Binuclear Transition Metal Complexes of Schiff Base Derived from 1-Amino-5-methyl-2,6-pyrimidine-dione and 2,3-Butanedione

“…Some other transition metal complexes have also been synthesized recently which show good biological activities viz. antimicrobial, DNA interaction and antitumor 8,9 . In view of these importance of metal complexes, we report herein preparation, characterization and in vitro antimicrobial activity of binuclear transition metal complexes of a novel Schiff base ligand derived from 1-amino-5-methyl-2,6-pyrimidine-dione and 2,3-butanedione.…”