Synthesis, Characterization and Antimicrobial Studies of Novel Binuclear Transition Metal Complexes of Schiff Base Derived from 1-Amino-5-methyl-2,6-pyrimidine-dione and 2,3-Butanedione

Singh, Netra Pal; Srivastava, Abhay Nanda

doi:10.14233/ajchem.2013.13484

Cited by 18 publications

(1 citation statement)

References 24 publications

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“…[1][2][3][4] In general, the complexation of organic ligands with most transition metal atoms influences their antibacterial activities. [5][6][7] In recent years, copper complexes have been extensively used in antibacterial agents. [8][9][10] At this point of view and in continuation of work on the study of metal complexes, herein we report a novel tetranuclear copper complex, [Cu 4 L 2 (m-Br) 2 Br 2 ], where L is the dianionic form of 1-methoxy-1,3-dipyridin-2-ylpentane-1,3-diol.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Crystal Structure, and Biological Property of a Novel Tetranuclear Copper(II) Complex

Zhou

Meng

et al. 2015

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-

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The reaction of 2-acetylpyridine, cyclopentylamine, and copper(II) bromide in methanol resulted in the tetranuclear copper(II) complex [Cu 4 L 2 (m-Br) 2 Br 2 ], where L is the dianionic form of 1-methoxy-1,3-dipyridin-2-ylpentane-1,3-diol. The complex was characterized by elemental analysis and IR spectroscopic method in the solid state. Single-crystal X-ray analysis was performed, which indicated that the complex possesses crystallographic twofold rotation axis symmetry. The complex crystallizes in the tetragonal space group P4 3 2 1 2 with unit cell dimensions a D b D 8.963 (1) A , c D 49.013(1) A , V D 3937.5(8) A 3 , Z D 4, R 1 D 0.0665, and wR 2 D 0.1397. The outer two Cu atoms are in tetrahedrally distorted square planar geometry. The inner two Cu atoms are in distorted square pyramidal geometry. Thermal behavior and biological property on the bacteria strains B. subtilis, E. coli, and S. aureus of the complex were studied.

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Section: Introductionmentioning

confidence: 99%

Synthesis, Crystal Structure, and Biological Property of a Novel Tetranuclear Copper(II) Complex

Zhou

Meng

et al. 2015

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-

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Design, synthesis, characterization and biological studies of copper(II) complexes with 2‐aminobenzimidazole derivatives as biomimetic agents

Joseph

Suman

Balakrishnan

2016

Applied Organom Chemis

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Four novel copper(II) complexes of 2‐aminobenzimidazole derivatives (obtained from the Knoevenagel condensation of acetylacetone (obtained from acetylacetone and halogen‐substituted benzaldehydes) and 2‐aminobenzimidazole) were synthesized. They were characterized using elemental analysis, molar conductance measurements, and fast atom bombardment mass, Fourier transform infrared, NMR, UV–visible and electron paramagnetic resonance spectroscopies. On the basis of the spectral studies, a distorted square planar geometry was assigned for all the complexes. The antibacterial screening of the ligands and their complexes revealed that all the complexes had higher activities than the free ligands. Superoxide dismutase and antioxidant activities of the copper complexes were also studied. The shifts in ΔEp, E1/2, Ipc and Ipa values were explored for the interaction of the complexes with calf thymus DNA using the electrochemical technique.

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Nanosized metal or silicon oxides and L‐proline or 4‐hydroxy‐L‐proline in stereoselective synthesis of a dihydropyrimidinethione podand

Filatova

Федорова

Овчинникова

et al. 2023

Applied Organom Chemis

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The stereoselective Biginelli reaction involving a CH-active podand, thiourea, and benzaldehyde using nanosized metal oxides (NiO, Fe 3 O 4 , CuO, Al 2 O 3 , SiO 2 , and TiO 2 -SiO 2 ), Brönsted acid, and commercially available chiral inductors (L-proline or 4-hydroxy-L-proline) was studied. The target dihydropyrimidinethione-containing podand was obtained with an enantiomeric excess of 70% and a moderate yield under mild conditions in the presence of nanooxide NiO and 4-hydroxy-L-proline. The adsorption of initial reactants and chiral inductor on the surface of nickel nanooxide was studied by IR spectroscopy. The activating and coordinating effect of the nanosized metal oxide on the initial reagents leading to an increasing the chemoselectivity and stereoselectivity of the Biginelli reaction was shown. On the basis of

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Synthesis, Characterization and Antimicrobial Studies of Novel Binuclear Transition Metal Complexes of Schiff Base Derived from 1-Amino-5-methyl-2,6-pyrimidine-dione and 2,3-Butanedione

Cited by 18 publications

References 24 publications

Synthesis, Crystal Structure, and Biological Property of a Novel Tetranuclear Copper(II) Complex

Synthesis, Crystal Structure, and Biological Property of a Novel Tetranuclear Copper(II) Complex

Design, synthesis, characterization and biological studies of copper(II) complexes with 2‐aminobenzimidazole derivatives as biomimetic agents

Nanosized metal or silicon oxides and L‐proline or 4‐hydroxy‐L‐proline in stereoselective synthesis of a dihydropyrimidinethione podand

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