Synthesis, Characterization, and Cytotoxicity of Iron Oxide Nanoparticles

Abstract

In order to study the response of human breast cancer cells' exposure to nanoparticle, iron oxide ( -Fe 2 O 3 ) nanoparticles were synthesized by a simple low temperature combustion method using Fe(NO 3 ) 3 ⋅9H 2 O as raw material. X-ray diffraction studies confirmed that the resultant powders are pure -Fe 2 O 3 . Transmission electron microscopy study revealed the spherical shape of the primary particles, and the size of the iron oxide nanoparticles is in the range of 19 nm. The magnetic hysteresis loops demonstrated that the sample exposed ferromagnetic behaviors with a relatively low coercivity. The cytotoxicity of -Fe 2 O 3 nanoparticle was also evaluated on human breast cancer cells to address the current deficient knowledge of cellular response to nanoparticle exposure.

Synthesis, Characterization and in Vitro Evaluation of Manganese Ferrite (MnFe2O4) Nanoparticles for Their Biocompatibility with Murine Breast Cancer Cells (4T1)

“…Many preparation methods have been used across the globe in the process of synthesis of these magnetic nanoparticles, include sol-gel [13,14], flash combustion [15] citrate gel [16], co-precipitation [17,18], hydrothermal synthesis [19], sol-gel auto combustion [20], micro-emulsion [21] and low temperature combustion methods [22]. It was reported that the chemical routes are the most suitable to synthesize nanomagnetic particles, among them, the sol-gel self-combustion method has attracted considerable attention and said to be a flexible method to synthesize spinel MnFe2O4 nanoparticles.…”

“…In recent times, manganese ferrite nanoparticles synthesized by traditional ceramic methods [8][9][10] suffered from drawbacks like uncontrolled particle size, uniformity, poorly defined stoichiometric composition, the presence of impurities during ball milling, chemical inhomogeneity, contamination, and high calcination temperatures [11,12]. Many preparation methods have been used across the globe in the process of synthesis of these magnetic nanoparticles, include sol-gel [13,14], flash combustion [15] citrate gel [16], co-precipitation [17,18], hydrothermal synthesis [19], sol-gel auto combustion [20], micro-emulsion [21] and low temperature combustion methods [22]. It was reported that the chemical routes are the most suitable to synthesize nanomagnetic particles, among them, the sol-gel self-combustion method has attracted considerable attention and said to be a flexible method to synthesize spinel MnFe 2 O 4 nanoparticles.…”

Creation of Wood Dust during Wood Processing: Size Analysis, Dust Separation, and Occupational Health

“…Within wood mass processing, when abrading via sanding or other processing technologies, it is necessary to have knowledge of the properties of harmful chemical agents generated from wood waste, i.e., the wood dust. In particular, toxicology bases show how to study and handle them to eliminate the properties that are dangerous for employees (Andersen et al 1999;Kauppinen 2000;Lioy 2002;Douwes et al 2003;Acheson et al 1968;Pukkala 2009;Kanagesan et al 2013;Gašparík and Gaff 2013a,b) while not decreasing their working bioresources.com . "Wood dust separation," BioResources 11(1), 209-222.…”

Beneficial effect of Cu on Ti-Nb-Ta-Zr sputtered uniform/adhesive gum films accelerating bacterial inactivation under indoor visible light

“…By Inductive coupled plasma mass-spectrometry (ICP-MS) it is shown that a sample TNTZ-(Cu) 8 after the 5th cycle releases only 0.4 ppb (see Supplementary material 3). This amount is far below the cytotoxic level causing damage to mammalian cell as reported recently [16,17]. The Cu-release in the ppb-range allows for a stable performance of this photocatalyst during repetitive bacterial inactivation.…”

“…; TiO 2 -Cu and Cu, Ti, Nb and their oxides were developed and investigated for their antibacterial properties. Achache et al [13,14] have recently reported the mechanical properties of super-elastic Ti-based gum metal thin films showing increased bacterial inactivation properties and biocompatibility [15,16]. The present study focuses on the effect of copper content on the structure, morphology and mechanical properties of these asdeposited films.…”