Synthesis, characterization and crystal structure of oxovanadium(IV) complex with tridentate o-van-gly and bidentate phenanthroline

Synthesis, crystal structure, and DNA interaction studies of a mixed-ligand copper(II) complex of 1,10-phenanthroline and a Schiff base derived from isoleucine

“…In recent years, some ternary salicylaldehyde-amino acid Schiff base complexes of copper(II) with phen and bipy co-ligands have been found to exhibit good DNA binding, DNA cleaving [8], and antitumor activity as well as potential for tumor radio-imaging [9]. In our previous work, we have synthesized and structurally characterized some amino Schiff base complexes [10][11][12]. In this work, we have synthesized and characterized a new ternary copper(II) complex bearing a Schiff base ligand derived from L-isoleucine plus 1,10-phenanthroline co-ligand.…”

A ternary copper(II) complex for supramolecular assembly with double helices: synthesis, crystal structure, DNA-binding and DNA-cleavage properties

“…Copper is one of the first-row transition metals and a bioessential element with relevant oxidation states, and its amino acid Schiff base complexes have received much attention [21,22]. In our previous work, we have synthesized and structurally characterized some amino Schiff base complexes [23][24][25]. In this communication, we report the synthesis and structural characterization of a new ternary copper(II) complex with a chiral amino acid Schiff base ligand [naph-ser: a Schiff base derived from 2-hydroxy-1-naphthaldehyde and L-serine] and planar N, N-donor heterocyclic ligand [bipy: 2,2 0 -bipyridine] and its self-assembly pattern via intermolecular hydrogen bonds leading to a double left-handed helical superstructure, as well as the DNA-binding and DNA-cleavage properties of this new complex.…”

An unexpected oxovanadium(IV) complex with in situ generated lactone ligand: Synthesis, crystal structure and DNA-binding property

“…In our previous work, we have synthesized and structurally characterized some oxovanadium complexes with multidentate Schiff base ligand and 1, 10-phenanthroline [25][26][27][28][29][30]. To continue our research in this project, we designed a new aminophenol-based multifunctional Schiff base ligand K 2 HL 1 (K 2 HL 1 = potassium 2-(((2-hydroxynaphthalen-1-yl)methylene)amino)pentanedioate) to construct potential oxovanadium-based material and drug.…”

“…However, this type of complex is not stable in the absence of other ligands. Efforts have been made to stabilize vanadium-amino acid complexes by using another ligand, such as a Schiff base of an amino acid [10][11][12]. On the other hand, amino acid Schiff bases and their first-row transition metal complexes exhibit fungicidal, bactericidal, antiviral, and antitubercular activity [13][14][15][16][17].…”

“…On the other hand, amino acid Schiff bases and their first-row transition metal complexes exhibit fungicidal, bactericidal, antiviral, and antitubercular activity [13][14][15][16][17]. Furthermore, oxovanadium complexes, especially with phenanthroline ligands, exhibit potent antitumor activity [18,19], DNA binding and DNA-photocleavage activities [20][21][22][23][24].In our previous work, we have synthesized and structurally characterized some oxovanadium complexes with multidentate Schiff base ligand and 1, 10-phenanthroline [25][26][27][28][29][30]. To continue our research in this project, we designed a new aminophenol-based multifunctional Schiff base ligand K 2 HL 1 (K 2 HL 1 = potassium 2-(((2-hydroxynaphthalen-1-yl)methylene)amino)pentanedioate) to construct potential oxovanadium-based material and drug.…”