Synthesis, characterization, and controllable drug release of pH-sensitive hybrid magnetic nanoparticles

Zhou, Lilin; Yuan, Jinying; Yuan, Weizhong; Sui, Xiaofeng; Wu, Sizhu; Li, Zhaolong; Shen, De-Zhong

doi:10.1016/j.jmmm.2009.04.020

Cited by 79 publications

(35 citation statements)

References 33 publications

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“…In addition, there are a weak absorption bands at wave number 1627, 1635 and around 3400 cm -1 which are the stretching vibration of OH groups on the surface of the magnetite indicating that the crystallization process was complete [16], [8]. But with the obvious appear of -OH groups on UMco shows that Fe(OH) 2 , Fe(OH) 3 and FeOOH formed as a result of hydrolisation on the surface of Fe 3 O 4 [12].…”

Section: Resultsmentioning

confidence: 98%

“…After 3 h aging, the products were collected by external magnet, washed with distilled water to neutral pH and then dried at 60°C to obtain mechanical magnetite nanoparticles (MMco) [15]. For reverse co-precipitation method, the mixed FeCl 3 …”

Section: A Reagentmentioning

confidence: 99%

“…Magnetite is highly preferred for many applications such as drug carrier [2], drug release [3], cancer therapy [4], a proton exchange membrane [5] and the heavy metal adsorbent [6]. Main advantage of using magnetic adsorbent is that the magnetic adsorbent is nontoxic and can be reused and easily separated from the solution by an external magnet [7].…”

Section: Introductionmentioning

confidence: 99%

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Synthesis and Characterization of Magnetites Obtained from Mechanically and Sonochemically Assissted Co-precipitation and Reverse Co-precipitation Methods

Sulistyaningsih¹,

Santosa²,

Siswanta³

et al. 2017

IJMMM

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Abstract-It has been examined the physical and chemical properties of magnetite synthesized mechanically and sonochemically by co-precipitation and reverse co-precipitation methods. Ammonia solution was used as precipitating agent to adjust the pH of the suspension to reach 11. Characterization of the synthesized magnetites was conducted using the Fourier Transform Infrared Spectroscopy (FTIR), the X-ray diffraction (XRD), Scanning electron microscopy (SEM), and Vibrating Sample Magnetometer (VSM). The characterization results showed that the crystallinity of magnetites synthesized by the ordinary mechanically assisted co-precipitation was higher than that of magnetites synthesized by mechanically assisted reverse-co-precipitation. The involvement of sonochemical treatment instead of mechanical treatment gave smaller and more homogeneous crystal size. The morphology of magnetites was spherical and agglomerated with homogeneous size distribution.

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Section: Resultsmentioning

confidence: 98%

Section: A Reagentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Synthesis and Characterization of Magnetites Obtained from Mechanically and Sonochemically Assissted Co-precipitation and Reverse Co-precipitation Methods

Sulistyaningsih¹,

Santosa²,

Siswanta³

et al. 2017

IJMMM

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“…(Compound 1-9). Alkaline precipitation of magnetite nanoparticles was performed as described in the literature [16] . The aqueous suspension was washed several times with deionized water and methanol.…”

Section: Preparation Of Bib-functionalized Magneticnanoparticlesmentioning

confidence: 99%

Preparation of Magnetic Polyimidazolium Microspheres by Surface-Initiated ATRP

Li¹,

Li²,

Zhou³

et al. 2017

dtmse

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Abstract. Narrow-disperse magnetic microspheres were prepared by alkaline coprecipitation of Fe 2+ and Fe 3+ ions within poly (acrylic acid-divinylbenzene) microspheres that were prepared by distillation-precipitation copolymerization. Magnetic microspheres with polyimidazolium that contain imidazolium groups were prepared by graft copolymerization of vinylimidazole and 1-chlorobutane via surface-initiated atom transferradical polymerization (SI-ATRP) from the magnetic microsphere surfaces. The magnetic polyimidazolium microspheres with an initiator group for copper-mediated atom transfer radical polymerization, well defined diblock copolymer brushes consisting of polyimidazolium were obtained by using the initial homopolymer brushes as the macro initiators for the ATRP of the second monomer. Transmission electron microscopy (TEM) displayed that the average particle size was 20 nm in diameter with some nanoaggregation observed. Fourier-transform infrared (FTIR) characterizated the surface modification process of magnetic microspheres (MMPs).

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“…The drug release study demonstrated that drug release was slow without magnetic field, and became rapid under the magnetic field [87]. Besides incorporation of temperature-responsive polymers, magnetic nanoparticles are also usually combined with pH-responsive polymers to obtain magnetic/pH-sensitive nanoparticles [91][92][93][94][95]. For example, Guo et al prepared magnetic/pH-responsive nanoparticles with magnetic cores and pH-responsive poly(glycerol monomethacrylate)-blockpoly(methacrylic acid)-block-polyoxyethylene(PGMA-b-PMAA-b-PEO) shells [91].…”

Section: Magnetic/(thermal or Ph)-responsive Nanoparticlesmentioning

confidence: 99%

Stimulus-responsive polymeric nanoparticles for biomedical applications

Dong

Wang

et al. 2010

Sci. China Chem.

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Polymeric nanoparticles with unique properties are regarded as the most promising materials for biomedical applications including drug delivery and in vitro/in vivo imaging. Among them, stimulus-responsive polymeric nanoparticles, usually termed as "intelligent" nanoparticles, could undergo structure, shape, and property changes after being exposed to external signals including pH, temperature, magnetic field, and light, which could be used to modulate the macroscopical behavior of the nanoparticles. This paper reviews the recent progress in stimulus-responsive nanoparticles used for drug delivery and in vitro/in vivo imaging, with an emphasis on double/multiple stimulus-responsive systems and their biomedical applications.polymer, stimulus-responsive nanoparticles, drug carrier, cellular imaging

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Synthesis, characterization, and controllable drug release of pH-sensitive hybrid magnetic nanoparticles

Cited by 79 publications

References 33 publications

Synthesis and Characterization of Magnetites Obtained from Mechanically and Sonochemically Assissted Co-precipitation and Reverse Co-precipitation Methods

Synthesis and Characterization of Magnetites Obtained from Mechanically and Sonochemically Assissted Co-precipitation and Reverse Co-precipitation Methods

Preparation of Magnetic Polyimidazolium Microspheres by Surface-Initiated ATRP

Stimulus-responsive polymeric nanoparticles for biomedical applications

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